| DC11356 |
Caspase-9 Chromogenic Substrate I |
Ac-LEHD-pNA is a substrate for caspase-9.1 Caspase-9 preferentially binds to and cleaves the Leu-Glu-His-Asp (LEHD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. |
|
| DC8941 |
Aclidinium bromide
Featured
|
Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). |
|
| DC23795 |
ACO1 |
ACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM, displays >200-fold selectivity against other Hsp90 isoforms. |
|
| DC10492 |
ACSS2 inhibitor
Featured
|
ACSS2 inhibitor is a novel ACSS2 inhibitor. |
|
| DC20640 |
ACT 709478 |
ACT 709478 is a potent, selective, orally-bioavailable, brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively. |
|
| DC21986 |
ACT-281959 |
ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
|
| DC7997 |
ACTB-1003
Featured
|
ACTB-1003 is a potent inhibitor of FGFR1 with IC50 <10 nM in FGFR-1 biochemical assay; more information can be find in Patent WO/2007/064883A2, Example 12. |
|
| DC20235 |
Ac-WEHD-pNA
Featured
|
Ac-WEAD-pNA is a colorimetric substrate for caspase-1 and caspase-4. |
|
| DC22659 |
ACY-775 |
ACY-775 (ACY775) is a potent and specific HDAC6 inhibitor (IC50=7.5 nM) with improved brain bioavailability. |
|
| DC20301 |
ADAMTS-5 inhibitor 15f |
ADAMTS-5 inhibitor 15f is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
|
| DC20302 |
ADAMTS-5 inhibitor 8 |
ADAMTS-5 inhibitor 8 is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
|
| DCAPI1013 |
Adapalene |
Adapalene |
|
| DC9362 |
Adarotene |
Adarotene (ST1926) is an effective apoptosis inducer and surprisingly produced DNA damage.ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells.
IC50 value: 0.12 uM (LNCaP cell) [1]
Target: Apoptosis inducer; Antican |
|
| DC20642 |
ADC-3680 |
ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
|
| DC21294 |
MK-1029 |
ADC-3680 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
|
| DC4155 |
Adefovir Dipivoxil
Featured
|
Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. |
|
| DC10745 |
Adelmidrol
Featured
|
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid. |
|
| DC10244 |
Ademetionine disulfate tosylate |
Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. |
|
| DCAPI1268 |
Adenosine (Adenocard) |
Adenosine (Adenocard) |
|
| DC20163 |
Adenosine 5'-monophosphate monohydrate; 5'-Adenylic acid;5'-AMP |
Adenosine 5'-monophosphate monohydrate (5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). |
|
| DC20303 |
Adhesamine |
Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth. |
|
| DC10685 |
Adipamidoxime(NSC 70868)
Featured
|
Adipamidoxime(NSC 70868) is a new bioactive compoud. |
|
| DCAPI1201 |
Adiphenine HCl |
Adiphenine HCl |
|
| DC12091 |
AdipoRon hydrochloride
Featured
|
AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively. |
|
| DC7049 |
AdipoRon
Featured
|
AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM) and AdipoR2(Kd=3.1 uM). |
|
| DC20644 |
ADM 12 |
ADM 12 (ADM_12. |
|
| DC9324 |
Adoprazine |
Adoprazine, a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
|
|
| DC12115 |
Adrenomedullin (AM) (1-52), human TFA (Human adrenomedullin-(1-52)-NH2 (TFA)) |
Adrenomedullin (AM) (1-52), human (TFA) affects cell proliferation and angiogenesis in cancer. |
|
| DC20645 |
ADT-094 |
ADT-094 (ADT094) is a novel, non-COX inhibitory sulindac derivative that potently and selectivity inhibits colon tumor cell growth by inhibiting PDE5 and PDE10 with IC50 of 2.4 uM and 0.5 uM, respectively. |
|
| DC10577 |
ADT-OH
Featured
|
ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. |
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