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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC20171 Alloxazine;Isoalloxazine Alloxazine is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.
DC12060 all-trans-4-Oxoretinoic acid all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).
DCAPI1478 Almotriptan Almotriptan
DCAPI1579 Alogliptin Alogliptin
DC5076 Alogliptin Benzoate Featured Alogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class. A randomized clinical trial reporting in 2011 aimed to determine the efficacy and safety of alogliptin versus placebo and voglibose among newly diagnosed Type 2 diabete
DC10735 Alovudine Featured Alovudine is a DNA polymerase subunit gamma-1 (POLG) inhibitor, shows promise for treating AML.
DC9920 alpha-Hederin Featured alpha-hederin is a water-soluble pentacyclic triterpenoid saponin, possessing several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation.
DC23079 α-mangostin Featured Alpha-Mangostin has neuroprotective, anti-cancer, antifungal, neuroprotective, renoprotective, antioxidant and anti-inflammatory activities.
DC20940 Alprazolam Alprazolam (D-65MT, U 31889) is a triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities.
DC26001 Alprenolol Featured Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist.
DCAPI1328 Alprostadil(Caverject) Featured Alprostadil(Caverject) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.
DC12656 Alrestatin Featured Alrestatin is an AKR (aldose reductase) inhibitor, which attaches molecules to the active site of the NADP+/enzyme complex in a stacked formation.
DC8366 ALS22335 Featured ALS-22335 is an anti-virus compound.
DC23098 ALS-8112 ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase(IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases.
DC23144 ALS-8176 ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM.
DCAPI1290 Altretamine (Hexalen) Altretamine (Hexalen)
DC7079 Alvelestat (AZD9668) Featured Alvelestat (AZD9668) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE.
DCAPI1250 Alverine Citrate Alverine citrate is a drug used for functional gastrointestinal disorders.
DC23849 ALW-II-49-7 ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2).
DC23604 ALX-5407 hydrochloride Featured ALX-5407 is a potent, selective, orally active inhibitor of GlyT1 glycine transporter with IC50 of 3 nM.
DC22431 AM432 sodium AM 432 is potent, selective, orally active prostaglandin D2 receptor (DP2/CRTH2) antagonist with binding IC50 of 6 nM for hDP2.
DC23485 AM-5262 AM-5262 is a potent full GPR40 (FFA1) agonist with EC50 of 81 nM.
DC23435 AM-6226 AM-6226 (AM6226) is a potent, selective, orally bioavailable GPR40 (FFA1) full agonist with EC50 of 0.12 uM.
DC9447 AM679 AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.
DC8958 Amantadine HCl Amantadine Hydrochloride is an antiviral and an antiparkinsonian drug.
DC10372 Amcasertib(BBI503) Featured Amcasertib(BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways, including Nanog, by targeting stemness kinases.
DC20792 Amelubant Amelubant (BIIL284) is a potent, long-acting, orally active leukotriene B4 (LTB4) receptor antagonist, inhibits LTB4-induced mouse ear inflammation with ED50 of 0.008 mg/kg (p.o.).
DC7356 Ametantrone Featured Ametantrone is a new anthracenedione antineoplastic agents, produced a concentration-dependent inhibition of hepatic microsomal lipid peroxidation.
DC9457 AMG 837 (calcium hydrate) AMG 837 calcium hydrate is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.
DC20660 AMG-076 AMG-076 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) with binding IC50 of 0.6 nM, with dramatically reduced hERG liability (IC50>5 uM).

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