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Alovudine

  Cat. No.:  DC10735   Featured
Chemical Structure
25526-93-6
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More than 5000 active chemicals with high quality for research!
Field of application
Alovudine is a DNA polymerase subunit gamma-1 (POLG) inhibitor, shows promise for treating AML.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 25526-93-6
Chemical Name: 3'-Deoxy-3'-fluorothymidine
Synonyms: 3'-Deoxy-3'-fluorothymidine;3,-Deoxy-3,-fluoro Thymidine;3’-Deoxy-3’-fluoro Thymidine;3'-Fluoro-3'-deoxythymidine;Alovudine;1-(3'-Deoxy-3'-fluoro-b-D-pentofuranosyl)thymine;3'-Fluorodeoxythymidine;3'-Fluorothymidine;CL 184824;FLT;MIV 310;NSC 140025
SMILES: CC1=CN(C(NC1=O)=O)[C@H]2C[C@H](F)[C@H](O2)CO
Formula: C10H13N2O4F
M.Wt: 244.21962
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: 3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer[1].
References: [1]. Challapalli A, et al. 3'-Deoxy-3'-18F-fluorothymidine positron emission tomography as an early predictor of disease progression in patients with advanced and metastatic pancreatic cancer. Eur J Nucl Med Mol Imaging. 2015 May;42(6):831-40.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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