| DC8514 |
AMG-1
Featured
|
AMG-1 is a potent inhibitor of human c-Met and RON with IC50 values of 4 and 9 nmol/L respectively. |
|
| DC20661 |
AMG-1694 |
AMG1694 is a potent, small molecule Glucokinase (GK)-GKRP (GK regulatory protein) disruptor, does not block the GK binding site directly. |
|
| DC23850 |
AMG-458(AMG458;AMG 458) |
AMG-458 (AMG458) is a potent, selective, orally bioavailable c-Met inhibitor with Ki of 1.2 nM (human c-Met). |
|
| DC20664 |
AMG-548
Featured
|
AMG-548 is a potent and selective inhibitor of p38α with Ki of 0.5 nM, dispalys weak inhibition for p38β (Ki=3.6 nM), and >5,000-fold selectivity over p38γ and p38δ; shows >1,000-fold selectivity over other 36 kinases, and is efficacious in acute and chro |
|
| DC12430 |
AMG7703 |
AMG7703 (4-CMTB, AMG-7703) is an allosteric, selective agonist of FFAR2 (GPR43).. |
|
| DC8503 |
AMG-Tie2-1
Featured
|
AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM). |
|
| DC9548 |
Amicarbazone |
Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.
|
|
| DCAPI1263 |
Amidopyrine |
Amidopyrine is white crystalline substance used as an analgesic and antipyretic. |
|
| DCAPI1043 |
Amikacin hydrate |
Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. |
|
| DC8984 |
Aminoglutethimide |
Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM. |
|
| DC11324 |
Aminopeptidase N Inhibitor |
Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). |
|
| DC11193 |
Aminopyridine 2 |
Aminopyridine 2 (MPO inhibitor AP-2) is a novel potent, selective, orally available inhibitor of Myeloperoxidase (MPO), inhibits MPO peroxidase activity in vitro and in human plasma with IC50 of 0.16 and 1.9 uM, respectively. |
|
| DC20206 |
Amitriptyline；MK-230, N-750, Ro41575 |
Amitriptyline is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. |
|
| DC9181 |
Amlodipine Besylate |
Amlodipine besylate is a long-acting calcium channel blocker. |
|
| DCAPI1067 |
Ammonium Glycyrrhizinate (AMGZ) |
Ammonium Glycyrrhizinate (AMGZ) |
|
| DC20178 |
Pyrrolidinedithiocarbamate ammonium;APDC, PDTC
Featured
|
Ammonium pyrrolidine dithiocarbamate (PDTC) is a potent nuclear factor-κB (NF-κB) inhibitor that inhibits IκB phosphorylation, blocks NF-κB translocation to the nucleus and reduces the expression of downstream cytokines. |
|
| DC20188 |
Amodiaquine |
Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria. |
|
| DCAPI1343 |
Amorolfine HCl
Featured
|
Amorolfine hydrochloride is a antifungal reagent. |
|
| DC10698 |
Amoscanate
Featured
|
Amoscanate(nithiocyamine) is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans,and is also highly active against hookworm |
|
| DCAPI1158 |
Amoxicillin sodium (Amox) |
Amoxicillin sodium (Amox) |
|
| DCAPI1309 |
Ampicillin sodium |
Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family. |
|
| DC23111 |
Ampkinone |
Ampkinone is a novel small molecule activator of AMPK, stimulates the phosphorylation of AMPK via indirect activation of AMPK in various cell lines (2.7-fold at 10 uM). |
|
| DC11274 |
AMPPD
Featured
|
AMPPD, 1,2-dioxo-cyclohexane derivatives, is a new biochemistry ultrasensitive alkaline phosphatase substrate. |
|
| DC23625 |
AMR-2 |
AMR-2 is a highly potent, orally active, triple reuptake inhibitor of SERT, NET, and DAT with IC50 of 3.0, 3.1, and 8.3 nM, respectively. |
|
| DC7002 |
Amrubicin(SM-5887) |
Amrubicin(SM-5887) is a novel anthracycline derivative for treatment of bladder carcinoma. |
|
| DC9634 |
Amsacrine |
Amsacrine (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. |
|
| DC20088 |
Amuvatinib hydrochloride (MP470 hydrochloride; HPK 56 hydrochloride) |
Amuvatinib hydrochloride (MP470 hydrochloride) is a multi-targeted receptor tyrosine kinases inhibitor, which inhibits c-Kit (D816V), c-Kit (D816H), c-Kit (V560G), c-Kit (V654A), PDGFRα (D842V), and PDGFRα (V561D) with IC50s of 950 nM, 10 nM, 34 nM, 127 n |
|
| DC21995 |
AMXT-1501 |
AMXT-1501 (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination of with DFMO. |
|
| DC21996 |
AMXT-1501 tetrahydrochloride |
AMXT-1501 tetrahydrochloride (AMXT 1501, AMXT1501) is a novel potent polyamine transport inhibitor, synergistically reduces cell viability in NB cells in combination with DFMO. |
|
| DC23109 |
AMZ30 |
AMZ30 is a potent, selective, covalent inhibitor of the serine hydrolase protein phosphatase methylesterase-1 (PME-1) with IC50 of 0.6 uM, >100-fold selectivity over other SHs. |
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