| DC10245 |
Azelaic acid |
Azelaic acid is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity. |
|
| DC8338 |
Azeliragon（PF-04494700,TTP488）
Featured
|
Azeliragon is an oral, small-molecule inhibitor of RAGE. |
|
| DCAPI1590 |
Azelnidipine |
Azelnidipine is an L-type calcium channel protein inhibitor |
|
| DC20156 |
Azetidine-2-carboxylic acid
Featured
|
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent. |
|
| DC4141 |
Azocosterol 2HCL |
Azocosterol is a potential avian reproductive inhibitor. |
|
| DCAPI1225 |
Azomycin (2-Nitroimidazole) |
Azomycin (2-Nitroimidazole) |
|
| DC9818 |
Azoramide
Featured
|
Azoramide is a small-molecule modulator of the unfolded protein response with antidiabetic activity. |
|
| DC12497 |
(Z)-Azoxystrobin
Featured
|
Azoxystrobin is a systemic, broad-spectrum fungicide belonging to the class of methoxyacrylates,which are derived from the naturally-occurring strobilurins. |
|
| DC22953 |
AZSMO-23 |
AZSMO-23 (AZSMO 23, AZSMO23) is a potent hERG potassium channel (Kv11.1) activator that activates WT hERG pre-pulse and tail current with EC50 of 28.6 and 11.2 μM respectively. |
|
| DCAPI1341 |
Aztreonam (Azactam, Cayston) |
Aztreonam (Azactam, Cayston) |
|
| DC21570 |
Azvudine
Featured
|
Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM; inhibits RNA synthesis by HCV polymerases from either HCV genotypes 1a and 1b or containing S96T or S282T point mutations (IC50=10-100 nM). |
|
| DC23756 |
Aβ polymerization stimulator O4 |
Aβ polymerization stimulator O4 is an orcein-related small molecule can drive polymerization of amyloid-β (Aβ). |
|
| DC12114 |
B I09 |
B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM. |
|
| DC22010 |
B591 |
B591 (B-591) is a potent, specific pan-PI3K inhibitor with IC50 of 1.3/0.36/1.1/1.58 uM for PI3Kα/β/γ/δ, respectively. |
|
| DC22011 |
BAA473 |
BAA473 (BAA-473) is a bile acid analogue that functions as the first small molecule activator of the Pyrin inflammasome, induces secretion of IL18 in LPS-primed PBMCs. |
|
| DC10859 |
Baccatin III
Featured
|
Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). |
|
| DC20063 |
BACE1-IN-2 |
BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM. |
|
| DCAPI1066 |
Bacitracin zinc |
Bacitracin zinc |
|
| DC8858 |
Bafilomycin A1(Baf-A1)
Featured
|
Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. |
|
| DC20740 |
BAL30072 |
BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml. |
|
| DCAPI1046 |
Balofloxacin |
Balofloxacin |
|
| DC9562 |
Balsalazide |
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
|
|
| DC10502 |
BAPTA/AM(BAPTA-AM)
Featured
|
BAPTA/AM is a membrane permeable form of BAPTA, a selective chelator of Ca2+. |
|
| DC10564 |
BAR 502
Featured
|
BAR502 is a dual FXR and GPBAR1 agonist with IC50 values of 2 μM and 0.4 μM, respectively. |
|
| DC20317 |
Barbadin |
Barbadin is a small molecule that selectively inhibits the β-arrestin/β2-adaptin interaction (IC50=19.1/15.6 uM for β-arrestin1/2) without effect on the formation of receptor/β-arrestin complexes. |
|
| DC12663 |
Bax channel blocker(BAI-1)
Featured
|
Bax channel blocker is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity. |
|
| DC23719 |
BAY 1024767 |
BAY 1024767 (BAY1024767) is a higly potent antagonist of androgen receptor (AR) wild-type (IC50=46 nM) and mutant forms located in the AR ligand-binding domain (LBD). |
|
| DC20750 |
BAY 1143269 |
BAY 1143269 is a potent, selective, orally bioavailable inhibitor of MNK1 with enzyme IC50 of 40 nM at 2 mM ATP. |
|
| DC23386 |
BAY 1238097 |
BAY 1238097 is a novel BET bromodomain inhibitor with IC50 of 50 nM, inhibits the interaction between BRD4, BRD3 or BRD2 and H4 with IC50 values of 63 nM, 609 nM and 2430 nM in the NanoBRET assay. |
|
| DC20589 |
BAY 1251152
Featured
|
BAY 1251152 (VIP152
) is the first potent, selective, orally available PTEFb/CDK9 inhibitor with biochemical IC50 of 9 nM and MOLM13 cell IC50 of 29 nM, displays> 50-fold selectivity against other CDKs. |
|
