| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21669 | SNAP 5114 | A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively. |
|
| DC20497 | PGRMC2-IN-25 | A gain-of-function ligand for PGRMC2 (progesterone receptor membrane component 2) to promote adipogenesis. |
|
| DC21363 | Lucerastat | A galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM). |
|
| DC22490 | 3-Bromopyruvic acid Featured | A glycolytic inhibitor that inhibits hexokinase II activity, suppresses ATP production, and induces endoplasmic reticulum (ER) stress. |
|
| DC21844 | Carbenoxolone | A glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.. |
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| DC21845 | Carbenoxolone disodium | A glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.. |
|
| DC22527 | Cyclic somatostatin Featured | A growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. |
|
| DC22347 | Penciclovir Featured | A guanosine analogue antiviral agent used for the treatment of various herpesvirus (HSV) infections. |
|
| DC22358 | Valproic acid sodium salt | A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
|
| DC22359 | Valproic acid | A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
|
| DC23983 | Pyraclonil | A herbicide agent. . |
|
| DC24171 | Furilazole | A herbicide safener for gramineous crops.. |
|
| DC22635 | SPDP Featured | SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker u |
|
| DC25080 | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. |
|
| DC22860 | Saframycin A | A heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro. |
|
| DC23757 | MLS-000532223 | A high affinity, selective inhibitor of Rho family GTPases with EC50 of 16-120 uM. |
|
| DC23268 | MIV 150 | A high-affinity, allosteric HIV-1 and HIV-2 reverse transcriptase inhibitor (NNRTI) with EC50 of 1 nM. |
|
| DC21592 | ML165 | A high-affinity, selective platelet integrin αIIbβ3 receptor antagonist with IC50 of 96 nM. |
|
| DC22429 | 4-BBPB Featured | A highly potent agonist of σ1 receptor with Ki of 0.8 nM. |
|
| DC22523 | 3-Deazaneplanocin A hydrochloride | A highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
|
| DC23476 | MRS-2500 | A highly potent and selective antagonist of the platelet P2Y1 receptor with Ki of 0.78 nM. |
|
| DC23477 | MRS-2500 tetraammonium | A highly potent and selective antagonist of the platelet P2Y1 receptor with Ki of 0.78 nM. |
|
| DC21604 | SA-57 | A highly potent and selective dual FAAH/MAGL inhibitor with IC50 of 1-3 nM against FAAH, inhibits mouse (IC50=410 nM) and human (IC50=1.4 uM) MAGL. |
|
| DC11765 | GRK2-IN-115h hydrochloride | A highly potent and selective GRK2 inhibitor with IC50 of 18 nM. |
|
| DC25060 | XDM-CBP | A highly potent and selective inhibitor of CBP/p300 bromodomain with Kd of 0.23/0.47 uM respectively, with high selectivity over all other BD families, including the BET family. |
|
| DC21649 | Volixibat potassium | A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).. |
|
| DC21648 | Volixibat | A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).. |
|
| DC9843 | AKR1C3 Inhibitor 5f Featured | A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. |
|
| DC22436 | JDTic | A highly potent and selective kappa Opioid receptor (KOR) antagonist with Ki of 0.3 nM. |
|
| DC22674 | TCV-309 | A highly potent and selective platelet activating factor (PAF) antagonist. |
|
