Cat. No. | Product name | CAS No. |
DC22678 |
Acebutolol
A cardioselective beta blocker for the treatment of hypertension and arrhythmias.. |
37517-30-9 |
DC22489 |
Acebutolol hydrochloride
Featured
Acebutolol HCl is a cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. |
34381-68-5 |
DC22875 |
Hexamethylene bisacetamide
A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade. |
3073-59-4 |
DC11648 |
2-D08
Featured
A cell permeable, mechanistically unique inhibitor of protein sumoylation. |
144707-18-6 |
DC20340 |
Chromeceptin
Featured
A cell-permeable benzochromene that selectively impairs the viability and growth of IGF2-overexpressing hepatocellular carcinoma cells, binds to MFP-2, stimulates the expression of IGFBP-1 and SOCS-3 through activation of STAT6. |
331859-86-0 |
DC20471 |
Naphthol AS-E
A cell-permeable inhibitor of the KIX-KID interaction and CREB-mediated gene transcription (IC50=2.26 uM). |
92-78-4 |
DC21591 |
Ru360
A cell-permeable mitochondrial calcium uptake inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM. |
|
DC22594 |
D-JNKI-1
A cell-permeable peptide inhibitor of JNK kinase. |
1445179-97-4 |
DC22590 |
Fumarase-IN-1
A cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle). |
1644060-37-6 |
DC23206 |
Bax inhibitor peptide V5
Featured
A cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. |
579492-81-2 |
DC20421 |
IQDMA
A cell-permeable, small molecule inhibitor of the transcription factor STAT5 that exhibits anticancer activity and inhibits the growth of A549, HL-60 and K562 cells with IC50 of 8, 5 and 8 uM, respectively.. |
401463-02-3 |
DC22378 |
DPH
Featured
A cell-permeable, small-molecule c-Abl kinase activator with pEC50 of 6.1(EC50=794 nM). |
484049-04-9 |
DC24193 |
BAPTA
Featured
BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. |
85233-19-8 |
DC22363 |
6-O-α-Maltosyl-β-cyclodextrin
A cellular cholesterol modifier that can form soluble inclusion complex with cholesterol. |
104723-60-6 |
DC20493 |
PDMP hydrochloride
A ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest. . |
73257-80-4 |
DC23222 |
Cinepazide
A cerebral vasodilator that acts as a calcium blocker. |
23887-46-9 |
DC22502 |
Ibrutinib-biotin
A chemical probe that consists of Ibrutinib linked to biotin via a long chain linker, has IC50 of 0.755-1.02 nM for Btk kinase. |
1599432-18-4 |
DC22344 |
Novaluron
Featured
A chemical with pesticide properties, belonging to the class of insecticides called insect growth regulators.. |
116714-46-6 |
DC22729 |
Flecainide
A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential. |
54143-55-4 |
DC24086 |
Azimilide
Featured
Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. |
149908-53-2 |
DC6912 |
Ethofibrate
Featured
A combination of clofibrate and niacin, used to treat hyperlipidaemias |
31637-97-5 |
DC23696 |
CGH2466
A combined adenosine receptor antagonist, p38 MAPK and PDE4 inhibitor, inhibits A1, A2b and A3 receptor (IC50=19, 21 and 80 nM), p38α, p38β and PDE4D (IC50=87, 400 and 22 nM). |
252198-68-8 |