DCC4811 |
Sn16713 |
Selective ligand of GC-rich sequences in DNA |
|
DCC4812 |
Sn-28049 |
Novel potent DNA-binding topoisomerase II-directed antitumor agent. |
|
DCC4813 |
Sn34037 |
Novel specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) |
|
DCC4814 |
Sn-38 Prodrug 3c |
Novel Bioorthogonal Prodrug of SN-38 with Fast Reaction Kinetics and High Releasing Efficiency In Vivo |
|
DCC4815 |
Snap-398299 |
Potent and selective GAL3 antagonist |
|
DCC4816 |
Snap-5089 |
Highly selective alpha1A-adrenoceptor antagonist |
|
DCC4817 |
Sniper(abl)-38 |
Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER), acting as a protein degradation inducer of oncogenic BCR-ABL protein |
|
DCC4818 |
Sniper(brd4)-1 |
Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of bromodomain-containing protein 4 (BRD4) |
|
DCC4819 |
Sniper(ch6) |
Novel fused proteins degrader of the His-tagged CRABP-II and Smad2 in cells |
|
DCC4820 |
Sniper(crabp)-11 |
Novel potent degrader of the mitochondrial CRABP-II protein |
|
DCC4821 |
Sniper(er)-87 |
Novel potent and selective degrader of the ERα protein |
|
DCC4822 |
Sniper(pde4)-9 |
Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of phosphodiesterase-4 (PDE4) |
|
DCC4823 |
Snri-h05 |
Novel potent serotonin and noradrenaline reuptake inhibitor (SNRI) with moderate 5-HT2A antagonist activity for anti-depression |
|
DCC4824 |
sns-oh |
Inducer of apoptosis in neuroblastoma cells through inhibition of AKT signaling pathway |
|
DCC4825 |
Snu-bp |
Novel agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines, potentiating interleukin-4-induced arginase-1 expression, promoting microglial polarization toward to an M2 anti-inflammatory phenotype |
|
DCC4826 |
Snx2-1-108 |
Highly selective inhibitor of CDK8 and its isoform CDK19 |
|
DCC4827 |
So1989 |
Novel macrophage modulator, inhibiting inflammation and M1 polarization of macrophages, restoring the balance between M1-polarized and M2-polarized macrophages in high fat diets (HFD)-induced obese mice resulting in the improvement of adipose inflammation |
|
DCC4828 |
soblidotin |
Inhibitor of tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis |
|
DCC4829 |
Sobuzoxane |
Orally available active prodrug of ICRF-154, interferring with topoisomerase II activity prior to the formation of intermediate cleavable DNA-enzyme complexes during the catalytic cycle resulting in tumor cell growth inhibition |
|
DCC4830 |
Sod1-derlin-1 Inhibitor 56-20 |
Novel potent inhibitor of SOD1-Derlin-1 interaction |
|
DCC4831 |
Sod1-derlin-1 Inhibitor 56-26 |
Novel potent inhibitor of SOD1-Derlin-1 interaction |
|
DCC4832 |
Sodelglitazar |
PPARdelta receptor agonist |
|
DCC4833 |
Sodium Dehydrocholate |
Hepatoprotective and choleretic agent |
|
DCC4834 |
Sodium Oxybate |
Narcolepsy agent, being used to treat catalepse and daytime sleepiness in patients with narcolepsy |
|
DCC4835 |
Solanidine |
Natural tumor antagonistic steroidal alkaloid, inducing typical cellular apoptotic hallmarks and cell cycle blockage at S-G2/M phase, activating nuclear import of DFF-40 mediated nucleosomal disruption and cell demise |
|
DCC4836 |
Solimastat |
Novel oral, broad-spectrum matrix metalloproteinase inhibitor (MMPI), being >10-fold more active than marimastat in inhibiting the processing of cell-bound TNF-alpha |
|
DCC4837 |
Somapacitan |
Novel long-acting, reversible albumin-binding growth hormone (GH) derivative for treatment of growth hormone dificiency |
|
DCC4838 |
Somatoprim |
Unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reducing GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours. |
|
DCC4839 |
Somcl-668 |
Novel potent and selective allosteric modulator of sigma-1 receptor |
|
DCC4840 |
Somcl-863 |
Novel, selective and orally bioavailable c-Met inhibitor, exhibiting antitumor activity both in vitro and in vivo |
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