Cat. No. | Product name | CAS No. |
DC22607 |
Masitinib mesylate
A potent tyrosine kinase inhibitor targeting c-Kit and PDGFR with IC50 of 0.15 and 0.05 uM in cell based assays. |
1048007-93-7 |
DC23995 |
Lck inhibitor 2
Featured
A potent tyrosine kinases inhibitor with IC50 of 13/9/3/26/2 nM for Lck/Btk/Lyn/Syk/Txk.. |
944795-06-6 |
DC22374 |
BMS-299897
A potent γ-secretase inhibitor that preferentially inhibits cleavage of the APP CTF cleavage with IC50 of 7.1 nM. |
290315-45-6 |
DC24011 |
(±)-BI-D
A potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase. |
1416258-16-6 |
DC20541 |
RUNX1-IN-17
A potent, allosteric inhibitor of CBFβ-RUNX1 interaction with IC50 of 3.2 uM in FRET assays. |
493028-20-9 |
DC23288 |
SMBA1
A potent, and selective Bax agonist (Ki=43.3 nM) that induces conformational changes in Bax by blocking S184 phosphorylation. |
906440-37-7 |
DC23992 |
FAAH inhibitor 1
A potent, and selective FAAH inhibitor with IC50 of 18 nM. |
326866-17-5 |
DC22748 |
UBP 302
A potent, and selective GluR5-subunit containing kainate receptor antagonist with Kd of 402 nM. |
745055-91-8 |
DC20475 |
Nek2 inhibitor 72
A potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM. |
|
DC23063 |
FAUC 1104
A potent, biased allosteric agonist of CXCR3 (pEC50=5.22) that activates solely G proteins, induces chemotaxis, but fails to induce receptor internalization or β-arrestin 2 recruitment.. |
1869983-86-7 |
DC23064 |
FAUC 1036
A potent, biased allosteric agonist of CXCR3 (pEC50=6.64), selectively induces chemotaxis and receptor internalization, and induces β-arrestin 2 recruitment without any stimulation of G proteins.. |
1869983-83-4 |
DC22801 |
MK2 inhibitor III
A potent, cell-permeable inhibitor of MK2 with IC50 of 8.5 nM. |
1186648-22-5 |
DC20868 |
CCG-203586
A potent, CNS-active Glucosylceramide synthase (GCS) inhibitor with IC50 of 27 nM. |
1430611-24-7 |
DC22472 |
Naltrexone
Featured
A potent, competitive antagonist for μ, κ, δ, and σ-opioid receptors with Ki of 0.0825 nM, 0.509 nM, and 8.02 nM, for MOR, KOR, and DOR, respectively. |
16590-41-3 |
DC22615 |
Rosuvastatin
A potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM. |
287714-41-4 |
DC20318 |
BCML
A potent, competitive inhibitor of quinine-activated bitter taste receptor T2R4 with IC50 of 59 nM.. |
113231-05-3 |
DC20702 |
Ilepatril
A potent, dual ACE-neutral endopeptidase (vasopeptidase) inhibitor with IC50 of 0.053 and 5.0 nM, respectively. |
473289-62-2 |
DC23394 |
Dual BET-Kinase inhibitor 3
A potent, dual BET bromodomain-kinase inhibitor with IC50 of 34, 1.1 and 1.1 nM for BRD4 BD1, JAK2 and FLT-3, respectively. |
1877286-69-5 |
DC20885 |
CGP-74514A
A potent, dual CDC-like kinase (CLK)/CDK inhibitor with IC50 of 148, 111, 104, 382 and 573 nM for CLK1, CLK2, CLK4, CDK1 and CDK4, respectively.. |
190653-73-7 |
DC24059 |
PI-103 hydrochloride
Featured
A potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively. |
371935-79-4 |
DC21562 |
Pz-1
A potent, dual pan-RET/VEGFR2 kinase inhibitor with IC50s of <1 nM for all RET, RET V804M and VEGFR2. |
1800505-64-9 |
DC20542 |
SA 16
A potent, dual PDK1 and Aurora kinase A inhibitor with IC50 of 416 and 35 nM, respectively. |
1919884-11-9 |