DC66278 |
DSPE-PEG-AC
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DSPE-PEG-AC phospholipid PEG derivative used in the preparation of liposomes, phospholipatized polyethylene glycol binding has both hydrophilic and hydrophobic properties.
Acrylate functionalized PEG is a common polymer for preparing biocompatible and biodegradable hydrogels and other biopolymers. Functionalized polyethylene glycol can be used to modify proteins, peptides, and materials, but also to increase solubility and stability, and reduce peptide and protein immunogenicity. It can also inhibit the non-specific combination of charged molecules to modify the surface. The product can be used in drug release, nanotechnology and new materials research, cell culture.
As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and pegylated modified functional coatings and other active compounds. |
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DC66279 |
DSPE-PEG-PEI
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Polyethyleneimine (PEI), also known as polyethyleneimine, is a water-soluble polymer. Colorless or yellowish viscous liquid, hygroscopic, soluble in water, ethanol, insoluble in benzene.
PEG-PEI, a copolymer of cationic poly (ethylene imide) (PEI) and polyethylene glycol (PEG), is a well-studied compound that significantly improves the delivery of oligonucleotides and nucleic acids (DNA, siRNA) in vitro and in vivo. By varying the MW of PEI and PEG, PEG-PEI drug conjugates, polymers, or nanoparticles with dynamic range of size, surface charge, and stability can be prepared, all of which are important for transfection efficiency.
PEI-PEG-DSPE, polyethylenimine-PEGyl-phospholipid is an AB block copolymer with phospholipids at the end of PEG that can be used in drug delivery systems. DSPE, 1, 2-distearoyl-SN-glycerol-3-phosphate ethanolamine is a synthetic phospholipid that can be used as a membrane material with solubility and is suitable for the development of liposomes and phospholipid complexes. |
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DC66280 |
DSPE-PEG-DOTA
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Macrocyclic ligands are ring complexes formed by multi-dentate ligands with O, N, P, S and other coordination atoms on the ring skeleton. The range of complexes is wide. According to their structural characteristics, complexes can be divided into the following types: simple complexes, chelates, polynuclear complexes, carbonyl complexes, metal clusters, sandwich complexes, and macrocyclic ligand complexes. |
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DC66281 |
DSPE-PEG-VE
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2-Distearoyl-sn-Glycero-3-Phosphoethanolamine(DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol, which has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes can be used for drug delivery, gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides,Liposomes. |
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DC66282 |
DOPE-mPEG (MW 5000)
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B40&" is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B40&"can be used in drug delivery research." |
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DC66283 |
DSPE-PEG-Silane
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DSPE-PEG-Silane is a surface-active phospholipid PEG derivative that can be used to modify the surfaces of glass, silica particles, and many other materials. DSPE-PEG-Silane is used as a PEG matrix in the preparation of pharmaceutical nanoparticles and can be used to control particle size and stability. It can also be applied to the preparation of biocompatible nanocarriers, such as nanoparticle carriers. Silyl groups are highly reactive to glass, silica, and many other materials. The reaction between alkoxysilane and the surface hydroxyl group makes the phospholipid PEG covalently attached to the surface of the modified material. Non-specific binding on the surface of PEG modified materials. |
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DC66284 |
DOPE-mPEG (MW 1000)
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DOPE-mPEG (MW 1000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG (MW 1000) can be used in drug delivery research. |
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DC66285 |
DPPE-MPEG (2000)
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DPPE-MPEG 2000 (1,2-DPPE-MPEG(2000)) is a PEG-modified lipids. DPPE-MPEG 2000 can reduce the nonspecific adsorption of protein and prolong circulation time in vivo. |
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DC66286 |
Di-n-decyldimethylammonium Bromide(DDAB)
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DDAB, also known as dodecyltrimethylammonium bromide, is a cationic surfactant with specific solubility, stability, and storage conditions.
1. Solubility: DDAB is soluble in water and organic solvents such as ethanol and chloroform. It forms clear solutions in water, but can become turbid at high concentrations or low temperatures. It has a higher solubility in organic solvents compared to CTAB.
2. Stability: DDAB is relatively stable under normal storage conditions. However, it can undergo degradation and lose its surfactant properties if exposed to extreme temperatures, humidity, or oxidizing agents for extended periods. It is important to store DDAB in a cool, dry place away from direct sunlight.
3. Storage conditions: DDAB should be stored in a tightly sealed container to prevent moisture absorption and contamination. It is recommended to store it at room temperature (around 20-25°C) or in a refrigerator (2-8°C) to maintain its stability and extend its shelf life. |
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DC66287 |
Cetrimonium bromide
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CTAB(Cetyltrimethylammonium bromide) is a quaternary ammonium surfactant commonly used in various fields such as chemistry, biology, and material science.
Structure: CTAB consists of a long hydrocarbon chain (cetyl group) attached to a positively charged nitrogen atom. The cetyl group provides hydrophobic properties to the molecule, while the positively charged nitrogen offers a hydrophilic head. |
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DC66288 |
DOSPA
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DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research. |
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DC66290 |
DSPE-PEG-Mannose
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DSPE (1,2-distearoyl-sn glycerol-3-phosphoethanolamine) is a saturated 18C phospholipid commonly used in liposome synthesis. Polyethylene glycol (PEG) conjugated DSPE has hydrophilicity and hydrophobicity, and can be used for drug delivery, gene transfection, and biomolecular modification. DSPE-PEG-Manose can be applied in medical research, drug release, nanotechnology and new material research, and cell culture. As well as ligand research, peptide synthesis support, grafting of polymer compounds, new materials, and polyethylene glycol modified functional coatings and other active compounds. |
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DC66291 |
DSPE-PEG-OPSS
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DSPE-PEG-OPSS, DSPE (1,2-distearoyl-sn-glycerol-3-phosphoethanolamine) is a saturated 18 carbon phospholipid, commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification. The PEG of phospholipid significantly improved the blood circulation time and stability of the capsule drug. Polyethylene glycol can enhance the solubility and stability, reduce the non-specific binding of charged molecules on the surface, and reduce the immunogenicity of polypeptides. Mercaptopyridine reacts with mercapto group to release pyridine ring and generate stable disulfide bond. |
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DC66292 |
DSPE-PEG-NPC
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DSPE-PEG-NPC is a linear heterobifunctional polyglycolation reagent containing DSPE phospholipids and NPC groups. It is a useful self-assembly reagent for preparing PEGylated liposomes or micelles, and also provides a combination of NPC group and thiol containing molecules. |
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DC66293 |
DSPE-PEG-N3
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DSPE-PEG-N3 is a click chemical PEG reagent. Azide group is easy to react with alkynyl group under the catalysis of copper catalyst. It can also react directly with DBCO without any catalyst. DSPE (1,2-distearoyl-sn-glycerol-3-phosphoethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification. The PEG of phospholipid significantly improved the blood circulation time and stability of the capsule drug. Polyethylene glycol can enhance the solubility and stability, reduce the non-specific binding of charged molecules on the surface, and reduce the immunogenicity of polypeptides.
Azide (- N3) can react with copper catalyzed alkynes in aqueous solution and be reduced to amino groups. Polyethylene glycol can increase solubility and stability. It can also inhibit the nonspecific binding of charged molecules on the modified surface.
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DC66294 |
DSPE-PEG-NBD
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DSPE-PEG-NBD is a fluorescent phospholipid PEG conjugate, which can be used as a lipid membrane probe. The excitation/emission wavelength of NBD is 460 nm/534 nm. |
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DC66295 |
DSPE-PEG-CY7
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Polyethylene glycol phospholipid is an excellent material to form liposomes, which can be used for gene transfection, vaccine delivery, drug transportation, and targeted drug delivery. Phospholipids are hydrophobic and hydrophilic. It can be used to modify protein drugs, peptide compounds, organic small molecule drugs, biological materials, etc. Cy7 labeled PEG derivatives are used for fluorescence tracing or fluorescence observation. |
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DC66296 |
DSPE-PEG-alkyne (MW 2000)
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The phospholipid polyethylene glycol alkyne (DSPE PEG Alkyne) can be used to modify proteins, peptides and other materials or small molecules. Alkynyl (- ALK) can react with copper catalyzed azide in aqueous solution. 2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol with hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes form high-quality materials, which can be used for drug delivery, gene transfection and vaccine delivery. PEGylated phospholipid can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides. |
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DC66297 |
DSPE
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DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. |
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DC66298 |
DSPE-PEG-Cy5(MW 2000 )
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The molecules can be labeled in the aqueous phase without organic solvents. Therefore, the product is especially suitable for labeling proteins that are easily denatured in the organic phase and proteins with low solubility.
Polyethylene glycol phospholipid liposomes form high-quality materials, which can be used for drug delivery, gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides. (DSPE) conjugated polyethylene glycol is a combination of phospholipids and polyethylene glycol, which has hydrophilicity and hydrophobicity. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces, such as antibodies and peptides.
Cyanogen dye cyanine is often used in biomolecular labeling, fluorescence imaging and other fluorescent biological analysis. Cy5 (sulfo-cyanine5) is a reactive dye used to label amino groups of peptides, proteins and oligonucleotides. Excitation wavelength (nm): 649, emission wavelength (nm): 670. |
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DC66299 |
DSPE-PEG-Cy5.5
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DSPE-PEG-Cy5.5is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. "&B26&"can be used in drug delivery research." |
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DC66300 |
ZM-306416 HCI
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DC66301 |
WHI-P97 HCl
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DC66302 |
PKC-theta inhibitor hcl
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PKCθ inhibitor is an inhibitor of PKCθ. |
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DC66303 |
STING-IN-3
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STING-IN-3 is an inhibitor of stimulator of interferon genes (STING). STING-IN-3 efficiently inhibits both hsSTING and mmSTING through covalently target the predicted transmembrane cysteine residue 91 and thereby block the activation-induced palmitoylation of STING. |
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AES-350 |
AES-350
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AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 μM and 0.245 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research. |
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DC66305 |
WAY-328133
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useful for the treatment of cystic fibrosis |
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DC66306 |
WAY-328182
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restore E-cadherin expression in the SW620 colon adenocarcinoma cell line |
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DC66307 |
WAY-328168
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antagonist of the NK3 receptor; altering the lifespan of a eukaryotic organism; |
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DC66308 |
WAY-299775
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potential leads for chaperone therapy for Gaucher disease |
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