DC60611 |
Compound 32 (HER2)
Featured
|
Compound 32 (HER2) is a potent and selective covalent inhibitor of HER2/WT and HER2/YVMA with IC50 of 49 nM and 42 nM, respectively. |
|
DC60612 |
IDOR-1117-2520
Featured
|
IDOR-1117-2520 is a selective and insurmountable antagonist of CCR6 with IC50 of 20 nM. |
|
DC66543 |
Pidobenzone
Featured
|
Pidobenzone is a dermatologic agent. |
|
DC66544 |
Pseudouridine 5'-triphosphate trisodium
Featured
|
Pseudouridine-5’-triphosphate (Pseudo-UTP) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties. |
|
DC66545 |
5-Bromo Brassinin
Featured
|
|
|
DC60613 |
LSN3441732
Featured
|
LSN3441732 is a dimeric compound and inhibits the formation of Lipoprotein(a) (Lp(a)) particles in vitro with IC50 of 0.18 nM. |
|
DC66546 |
R-Sirpiglenastat
Featured
|
R-Sirpiglenastat is the R- isomer of Sirpiglenastat(DRP-104).Sirpiglenastat (DRP104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response. |
|
DC66547 |
SL25 intermediate 16
Featured
|
|
|
DC60614 |
BIO-8169
Featured
|
BIO-8169 is a highly potent, selective, and brain-penetrant IRAK4 inhibitor with IC50 of 0.2 nM. BIO-8169 has an excellent PK profile, reduces the in vivo production of pro-inflammatory cytokines, and is tolerated in toxicity studies in rodents and dogs. |
|
DC60615 |
Nelutroctiv (CK-136)
Featured
|
Nelutroctiv (CK-136) is a novel cardiac troponin activator devoid of PDE-3 activity that demonstrates a wider pharmacodynamic window in vivo relative to a representative myosin activator, CK-138. |
|
DC60616 |
TERT activator compound tac
Featured
|
TAC is a TERT activator compound that upregulates TERT transcription via the MEK/ERK/AP-1 cascade. TAC alleviates neuroinflammation, increases neurotrophic factors, stimulates adult neurogenesis, and preserves cognitive function without evident toxicity, including cancer risk. |
|
DC66548 |
GalNAc-Lipid GL3
Featured
|
|
|
DC66549 |
GalNAc-NAG-37 Phosphoramidite
Featured
|
|
|
DC66550 |
GalNAc-Cluster-COOH
Featured
|
|
|
DC66551 |
GalNAc-Cluster-HHA-CE Phosphoramidite
Featured
|
|
|
DC66552 |
PAM-Acid derivatives
Featured
|
|
|
DC66553 |
PAM-Acid
Featured
|
|
|
DC66554 |
AdemC-GalNAc Phosphoramidite
Featured
|
|
|
DC66555 |
GalNAc-L96 Linker-Acid
Featured
|
|
|
DC66556 |
GalNAc PEG Cluster Phosphoramidite
Featured
|
|
|
DC66557 |
GalNAc-L96 Linker-Azide
Featured
|
|
|
DC66558 |
Propargyl PEG Linker Phosphoramidi
Featured
|
|
|
DC66559 |
Peracetylated GalNAc PEG linker-Azide
Featured
|
|
|
DC66560 |
GalNAc-L96-tert-butyl ester
Featured
|
GalNAc-L96-tert-butyl ester is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC66561 |
Peracetylated GalNAc succinimidyl pentanoate
Featured
|
|
|
DC66562 |
Peracetylated GalNAc-C3-Amine-1
Featured
|
|
|
DC66563 |
Peracetylated GalNAc-L96-Acid-2
Featured
|
|
|
DC66564 |
Peracetylated GalNAc PEG linker-Acid-1
Featured
|
|
|
DC66565 |
Peracetylated GalNAc-L96-Acid-1
Featured
|
|
|
DC66566 |
Peracetylated GalNAc-L96-Amide-1
Featured
|
|
|