A792 |
MilatuzuMab
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Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death. |
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A793 |
Iladatuzumab
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Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research. |
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A794 |
Polatuzumab
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Polatuzumab is a monoclonal antibody, which targets CD79b that is found on the surface of B cells. Polatuzumab sticks to the CD79b protein and delivers the chemotherapy compound into the cell. Polatuzumab can be used to synthesize Polatuzumab Vedotin, which is an antibody-drug conjugate (ADC) targeting CD79b . |
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A795 |
Genentech patent anti-CD83
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A796 |
Genentech patent anti-CD9
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A797 |
DCBY02
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A798 |
Ign523
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A799 |
Anti-CDCP1/CD318 Antibody (38 E11)
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A800 |
U.California patent anti-CDCP1
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A809 |
CM-24
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A801 |
Stem Centrx patent anti-Cadherin-1
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A802 |
RG-6125
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A803 |
10C12
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A804 |
Anti-CDH17/Cadherin-17 Antibody (PTA001_A4)
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A805 |
PF-03732010
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A806 |
DS-6000A
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A807 |
HKT288
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A808 |
Actoxumab
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Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB. |
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A810 |
Chaim Sheba Med. Cntr. patent anti-CEACAM1
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A811 |
Tusamitamab
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Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative). |
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A812 |
Labetuzumab
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Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy. |
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A813 |
Tinurilimab
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Tinurilimab (Bay 1834942) is an anti-CEACAM6 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors. |
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A814 |
NEO-201
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A815 |
Brown U. patent anti-CHI3L1
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A816 |
Academia Sinica patent anti-Clathrin Heavy Chain
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DC67161 |
MPEG-2000-DPPE Na
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DPPE-MPEG(2000) is a PEGylated form of 1,2-dipalmitoyl-rac-glycero-3-PE (DPPE). It has been used in the synthesis of anionic liposomes for drug redistribution and toxicity prevention. |
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DC67162 |
(S)-GSK-3685032
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(S)-GSK-3685032 is the isomer of GSK-3685032 (HY-139664), and can be used as an experimental control. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition. |
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DC67163 |
1-Piperazinecarboxylic acid, 4-[6-(methoxycarbonyl)-3-pyridinyl]-, 1,1-dimethylethyl ester
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DC67164 |
WAY-204688
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WAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122 ± 30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells. |
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DC67165 |
Benzamide, 2-[(4-hydroxyphenyl)amino]-4-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]-
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