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Cat. No. Product Name Field of Application Chemical Structure
A792 MilatuzuMab Featured Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death.
A793 Iladatuzumab Featured Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research.
A794 Polatuzumab Featured Polatuzumab is a monoclonal antibody, which targets CD79b that is found on the surface of B cells. Polatuzumab sticks to the CD79b protein and delivers the chemotherapy compound into the cell. Polatuzumab can be used to synthesize Polatuzumab Vedotin, which is an antibody-drug conjugate (ADC) targeting CD79b .
A795 Genentech patent anti-CD83 Featured
A796 Genentech patent anti-CD9 Featured
A797 DCBY02 Featured
A798 Ign523 Featured
A799 Anti-CDCP1/CD318 Antibody (38 E11) Featured
A800 U.California patent anti-CDCP1 Featured
A809 CM-24 Featured
A801 Stem Centrx patent anti-Cadherin-1 Featured
A802 RG-6125 Featured
A803 10C12 Featured
A804 Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) Featured
A805 PF-03732010 Featured
A806 DS-6000A Featured
A807 HKT288 Featured
A808 Actoxumab Featured Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB.
A810 Chaim Sheba Med. Cntr. patent anti-CEACAM1 Featured
A811 Tusamitamab Featured Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative).
A812 Labetuzumab Featured Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy.
A813 Tinurilimab Featured Tinurilimab (Bay 1834942) is an anti-CEACAM6 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors.
A814 NEO-201 Featured
A815 Brown U. patent anti-CHI3L1 Featured
A816 Academia Sinica patent anti-Clathrin Heavy Chain Featured
DC67161 MPEG-2000-DPPE Na Featured DPPE-MPEG(2000) is a PEGylated form of 1,2-dipalmitoyl-rac-glycero-3-PE (DPPE). It has been used in the synthesis of anionic liposomes for drug redistribution and toxicity prevention.
DC67162 (S)-GSK-3685032 Featured (S)-GSK-3685032 is the isomer of GSK-3685032 (HY-139664), and can be used as an experimental control. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.
DC67163 1-Piperazinecarboxylic acid, 4-[6-(methoxycarbonyl)-3-pyridinyl]-, 1,1-dimethylethyl ester Featured
DC67164 WAY-204688 Featured WAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122 ± 30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells.
DC67165 Benzamide, 2-[(4-hydroxyphenyl)amino]-4-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]- Featured

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