| DC60771 |
（+/-)-AC 7954 Hydrochloride
Featured
|
AC-7954 is a selective nonpeptidic urotensin receptor agonist (EC50: 300 nM at the human UII receptor). |
|
| DC67221 |
3'OMe-m7GpppAmpG (ammonium) solution (100mM)
Featured
|
3'OMe-m7GpppAmpG ammonium solution (100mM) is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization. |
|
| DC60772 |
MORF-627
Featured
|
MORF-627 is a potent, orally bioavailable, selective inhibitor that stabilizes the bent-closed form of αvβ6 with IC50 of 9.2 nM and shows good selectivity against αvβ1 and αvβ8 (230-fold and 340-fold, respectively. |
|
| DC60773 |
Protoporphyrin IX
Featured
|
Protoporphyrin IX is an organic compound, classified as a porphyrin, that plays an important role in living organisms as a precursor to other critical compounds like heme (hemoglobin) and chlorophyll. It is a deeply colored solid that is not soluble in water. The name is often abbreviated as PPIX. Protoporphyrin IX florescence from 5-ALA administration is used in fluorescent-guided surgery of glioblastoma. Protoporphyrin IX is an important precursor for synthesis of verteporfin, an approved photosensitizer. |
|
| DC60774 |
Monlunabant
Featured
|
Monlunabant, also known as INV-202, is a potent CB1R inverse agonist. INV-202 reduced glomerular injury, preserved podocyte structure and function, reduced injury to PTECs, and ultimately reduced renal fibrosis in a streptozotocin-induced diabetic nephropathy mouse model. |
|
| DC60775 |
HEC96719
Featured
|
HEC96719 is a tricyclic farnesoid X receptor agonist (FXR agonist) for treatment of non-alcoholic steatohepatitis. HEC96719 exhibits excellent potency superior to GW4064 and obeticholic acid in in vitro and in vivo assays of FXR activation. It also shows higher FXR selectivity and more favorable tissue distribution dominantly in liver and intestine. Preclinical data on pharmacokinetic properties, efficacy, and safety profiles overall indicate that HEC96719 is a promising drug candidate for NASH treatment. |
|
| DC67222 |
mPEG-5000-DPPE, Na
Featured
|
|
|
| DC67223 |
Monophosphoryl Lipid A-12
Featured
|
Monophosphoryl Lipid A-12 (MPLA-12) is a biochemical reagent. |
|
| DC67224 |
3D-Monophosphoryl Lipid (14)
Featured
|
3D-Monophosphoryl Lipid (14) (3D-MPL (14)) is a biochemical reagent. |
|
| DC67225 |
3D-MPL(12;16)
Featured
|
3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that can be used as a vaccine adjuvant to enhance the immunogenicity of vaccines[1]. |
|
| DC67226 |
3D-MPLA
Featured
|
3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) is a TLR agonist that can be used as an adjuvant for vaccines to enhance their immunogenicity. |
|
| DC67227 |
UM-3006
Featured
|
UM-3006 is a highly efficient TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. UM-3006 holds significant research and application potential in the fields of vaccine adjuvants and immune diseases. |
|
| DC67228 |
DSPE-PEG-Folate
Featured
|
DSPE-PEG-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research. |
|
| DC67229 |
DSPE-PEG-Mannose
Featured
|
DSPE-PEG-Mannose,1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethyleneglycol)-Mannose (sodium salt)is white solid for drug delivery systems, It is an active target material, Itcan be used as an antitumor drug carrier and active targeted delivery |
|
| DC67230 |
AYK005
Featured
|
AYK005 is a TLR7/8 immunologic adjuvant. |
|
| DC67231 |
AYK004
Featured
|
AYK004 is a TLR7/8 agonist that enhances immune responses by activating the TLR signaling pathway. AYK004 is an adenine derivative with a favorable hydrophilic-lipophilic balance, which improves the loading capacity and stability in immunoadjuvant systems such as liposomes, while reducing the side effects of the immunoadjuvant system in systemic immunity . |
|
| DC67232 |
AYK004-B1
Featured
|
AYK004-B1 is a TLR7 agonist (EC50=0.2265 nM). AYK004-B1 can be used to prepare immune adjuvants. |
|
| DC67233 |
AYK004-C1
Featured
|
AYK004-C1 is a TLR agonist. AYK004-C1 can be used to prepare immune adjuvants. |
|
| DC67234 |
CPG-1018
Featured
|
|
|
| DC67235 |
CPG 7909
Featured
|
|
|
| DC67236 |
QS-7
Featured
|
QS 7 (QS 7 Api) is a saponin compound that can be extracted from the Quillaja saponaria tree. QS 7 activates immune cells, enhances their antigen presentation ability and cytokine secretion. QS 7 can be used as vaccine adjuvant for immunostimulating, anti-tumor, and anti-infectious activities. |
|
| DC67237 |
TQL-1055
Featured
|
TQL-1055 is a semi-synthetic analog of the saponin adjuvant QS-21 (HY-101092) and can be used as a prophylactic vaccine adjuvant. TQL-1055 exhibits robust adjuvant activity for influenza antigens. TQL-1055 combined with the acellular pertussis vaccine (aP) shows good tolerance and enhances the antibody response to pertussis toxin (PT) in mice and rabbits. TQL-1055 is promising for research of chronic hepatitis B. |
|
| DC67238 |
KRN-7000(C34)
Featured
|
|
|
| DC67239 |
KRN-7000(S34)
Featured
|
|
|
| DC67240 |
KRN-7000(7DW8-5)
Featured
|
|
|
| DC67274 |
Cp2-S04
Featured
|
Cp2-SO4 is a phenylalanine derivative that acts as an inhibitor of interleukin-4-induced-1 (IL4I1), an enzyme implicated in immune regulation and tumor immune evasion. IL4I1 is an L-amino acid oxidase that promotes an immunosuppressive microenvironment by producing metabolites like H2O2 and kynurenine, which inhibit T-cell proliferation and function. Cp2-SO4 reverses IL4I1-dependent suppression of T-cell proliferation, making it a promising candidate for cancer immunotherapy and immune-related diseases. Its Ki value of 21.2 µM indicates its potency in blocking IL4I1 activity. |
|
| DC74630 |
Antiviral agent 17 |
Antiviral agent 17 is an anti-infection agent. |
|
| DC74631 |
JAK-IN-21 |
JAK-IN-21 (Example 4) is a selective and potent JAK inhibitor. |
|
| DC74632 |
Dimethylamiloride |
Dimethylamiloride is a Na(+)-H+ exchange inhibitor. |
|
| DC74633 |
TCMDC-137332 |
TCMDC-137332 is a compound that exhibits antimalarial activity against Plasmodium falciparum with an IC50 value of 7 nM. |
|
