| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| A1055 | Cosfroviximab Featured | Cosfroviximab (c13C6-FR1) is a mouse/human chimeric monoclonal antibody against Ebola virus glycoprotein (EBOV-GP). |
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| A1056 | Odesivimab Featured | Odesivimab is a human monoclonal antibody, targeting Ebola virus glycoprotein with a KD value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection. |
|
| A1057 | Anti-IAV Reference Antibody Featured |
|
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| A1058 | Navivumab Featured | Navivumab (CT-P23) is an influenza A virus hemagglutinin HA monoclonal antibody. neutralizes H1, H2, H5, and H9 influenza A viruses by binding to the stem fusion domain in HA2. |
|
| A1059 | Atoltivimab Featured | Atoltivimab (REGN3470), or maftivimab/odesivimab (Inmazeb) is the first Food and agent Administration (FDA)-approved monoclonal antibody to target Zaire ebolavirus (EBOVs) infection. |
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| A1060 | Muromonab Featured | Muromonab is a monoclonal antibody targeting the CD3 receptor. Muromonab can block all cytotoxic T cell function. Muromonab also as an immunosuppressant agent given to reduce acute solid organ transplant rejection. |
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| DC67212 | Acuitas Lipid III-25 Featured | Acuitas Lipid III-25 is an novel ionizable amine lipid used for mRNA delivery from Acuitas Therapeutics patent US 10,166,298 B2. It is an analgous of ALC-0315, showing higher activity than ALC-0315. |
|
| DC67213 | Acuitas II-10 Featured | Acuitas II-10 is an novel ionizable amine lipid used for mRNA delivery from Acuitas Therapeutics patent WO2016176330A1 |
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| DC67214 | Acuitas II-12 Featured | Acuitas II-12 is an novel ionizable amine lipid used for mRNA delivery from Acuitas Therapeutics patent WO2016176330A1 |
|
| DC67215 | Acuitas Lipid III-7 Featured | Acuitas Lipid III-7 is an novel ionizable amine lipid used for mRNA delivery from Acuitas Therapeutics patent US 10,166,298 B2. |
|
| DC67216 | L13 Featured |
|
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| DC67217 | Moderna Lipid compound 46 Featured | Moderna Lipid compound 46 is an novel ionizable amine lipid used for mRNA delivery from Moderna patent WO2017049245A2 |
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| DC67218 | Moderna Lipid compound 182 Featured | Moderna Lipid compound 182 is an novel ionizable amine lipid used for mRNA delivery from Moderna patent WO2017049245A2 |
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| DC67219 | L17 Featured |
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| DC60732 | VUF10166 Featured | VUF10166 is a potent and high-affinity 5-HT3 receptor antagonist, with Ki values of 0.04 nM (5-HT3A) and 22 nM (5-HT3AB). VUF10166 inhibits 5-HT-induced responses at 5-HT3A and 5-HT3AB receptors at nanomolar concentrations. At 5-HT3 receptor, VUF10166 at higher concentrations also acts as a partial agonist, with an EC50 of 5.2 μM. |
|
| DC60733 | F-1 Featured | F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. |
|
| DC60734 | MMBC Featured | MMBC is a sulfhydryl-sensitive fluorophore. |
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| DC60735 | ATP synthase inhibitor 1 Featured | ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels. |
|
| DC60736 | Mebeverine alcohol Featured | Mebeverine alcohol is a metabolite of Mebeverine, which is a musculotropic antispasmodic drug. |
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| DC60737 | Sunitinib Featured |
|
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| DC67220 | Acuitas Lipid II-10 Featured |
|
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| DC60738 | ROCK inhibitor-2 Featured | ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC50 of 75 nM. |
|
| DC60739 | WAY-213613 hydrochloride Featured | WAY-213613 (hydrochloride) is a potent and selective human EAAT2 inhibitor. WAY-213613 has potent EAAT2 inhibitory activity with an IC50 value of 85 nM. WAY-213613 can be used for the research of central nervous system. |
|
| DC60740 | DDD107498 succinate Featured |
|
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| DC60741 | AD57 hydrochloride Featured | AD57 hydrochloride is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src. |
|
| DC60742 | TAU-IN-1 Featured | TAU-IN-1 (compound 051) is a TAU protein inhibitor with an EC50 value of 325 nM. TAU-IN-1 can be used in the study of neurodegenerative diseases. |
|
| DC60743 | PLpro-IN-1 Featured | PLpro-IN-1 (Compound 2) is a SARS-CoV PLpro inhibitor (IC50: 8.7 μM). PLpro-IN-1 can be used for antiviral research. |
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| DC60744 | Cotoin Featured | Cotoin is a natural product isolated from the stem bark of Garcinia virgate. |
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| DC60745 | CC618 Featured | CC618 is a selective peroxisome proliferator-activated receptor (PPARβ/δ) antagonist that exhibits antagonism by covalently binding to PPARβ/δ receptors. |
|
| DC60746 | SCF29402 Featured |
|
