| DC9889 |
Kynurenic acid |
Kynurenic acid, a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist. |
|
| DC10669 |
KYP-2047
Featured
|
KYP-2047 is a very potent, selective inhibitor of Prolyl oligopeptidase (POP), also known as prolyl endopeptidase (PEP or PE). Ki = .023nM (porcine). |
|
| DC12332 |
KZR-504 |
KZR-504 is a highly selective and orally active inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. |
|
| DC12484 |
KZR-616
Featured
|
KZR-616 (KZR616) is a potent, selective dual immunoproteasome subunit LMP7/LMP2 inhibitor with IC50 of 39 nM/139 nM, weakly inhibits β5, MECL-1 and no acitivty against β1 subunit. |
|
| DC7934 |
L-006,235
Featured
|
L 006235 is a reversible and potent cathepsin K inhibitor that displays more than a 4000 fold selectivity over cathepsins B, L and S. |
|
| DC21217 |
L 873724 |
L 873724 is a potent and selective non-basic cathepsin K inhibitor with IC50 of 0.2 nM, shows no significant potency against Cat B, L, and S (IC50= 5239, 264, and 178 nM). |
|
| DC8987 |
L-Methyldopa |
L-(-)-α-Methyldopa hydrate is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. |
|
| DCAPI1001 |
L(+)-Rhamnose Monohydrate |
L(+)-Rhamnose Monohydrate |
|
| DC8578 |
L002(NSC764414)
Featured
|
L002 is a p300 inhibitor (IC50=1.98 μM) that inhibits p53 and histone acetylation. Suppresses STAT3 activation in vitro and suppresses tumor growth in some mouse cell lines. |
|
| DC2076 |
L-165041
Featured
|
L-165041 is a potent PPARδ agonist (Ki = 6 nM). |
|
| DC8136 |
L-189
Featured
|
L-189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki = 5 μM for DNA ligase I). |
|
| DC22070 |
L-257 |
L-257 (DDAH-1 inhibitor L-257) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM. |
|
| DC22071 |
L-291 |
L-291 (DDAH-1 inhibitor L-291) is a selective, competitive DDAH1 inhibitor with IC50 of <25 uM. |
|
| DC21215 |
L-338192 |
L-338192 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 29 uM in AlphaScreen assay. |
|
| DC23595 |
L-364373 |
L-364373 (R-L3) is a stereospecific activator of cardiac slowly activating delayed rectifier K+ current (IKs) and KV7.1 (KCNQ1) channels. |
|
| DC20041 |
L-5-Hydroxytryptophan (L-5-HTP; Oxitriptan)
Featured
|
L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydr |
|
| DC8790 |
L67
Featured
|
L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM. |
|
| DC8615 |
L-685,458
Featured
|
L-685,458 is a selective and Potent inhibitor of γ-secretase with IC50 value of 17 nM. |
|
| DC8159 |
L-701,324
Featured
|
L-701,324 is a selective antagonist at the glycine site of the NMDA receptor, counteracts haloperidol-induced muscle rigidity in rats. |
|
| DC8092 |
L-755,507
Featured
|
L-755,507 enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs). |
|
| DC8803 |
L-778123 HCl
Featured
|
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination. |
|
| DC8362 |
L-779,450
Featured
|
L-779,450 is a potent, ATP-competitive Raf (Raf kinase) inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. |
|
| DC11377 |
L-826,266 |
L-826,266 is a potent and selective competitive antagonist of the prostaglandin E2 receptor subtype EP3 (Ki = 0.8 nM). |
|
| DC9382 |
Lacidipine |
Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker. |
|
| DC8797 |
Lacosamide
Featured
|
Lacosamide (Vimpat; Erlosamide) is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. |
|
| DC20850 |
Lactimidomycin |
Lactimidomycin is a glutarimide antibiotic that has antifungal, antiviral and anti-cancer properties, acting as a direct inhibitor of protein translation in ribosomes. |
|
| DCAPI1184 |
Lactulose (Enulose) |
Lactulose (Enulose) |
|
| DC21218 |
LAF389 |
LAF389 is a potent methionine aminopeptidase (MetAP) inhibitor with IC50 of 800 nM for MetAP-2, inhibits both MetAp1 and 2, potently inhibits HUVEC proliferation with IC50 of 20 nM. |
|
| DCAPI1422 |
Lafutidine |
Lafutidine |
|
| DC9006 |
Lamotrigine |
Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channel. |
|
