DC3160 |
Montelukast Sodium
Featured
|
Montelukast belongs to a group of medications known as leukotriene receptor antagonists. |
|
DC8931 |
Mosapride |
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
|
DC12485 |
Mosedipimod |
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro. |
|
DC7200 |
Motesanib Diphosphate (AMG-706)
Featured
|
Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. |
|
DC10284 |
Motesanib
Featured
|
Motesanib is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret. |
|
DC8815 |
Motolimod (VTX-2337)
Featured
|
Motolimod (VTX-2337) is a novel TLR8 agonist that activates NK cells and augments ADCC. |
|
DC4226 |
Moxifloxacin hydrochloride
Featured
|
Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent. |
|
DCAPI1331 |
Moxonidine |
Moxonidine |
|
DCAPI1572 |
Moxonidine hydrochloride |
Moxonidine hydrochloride |
|
DC10326 |
Mozavaptan |
Mozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM. |
|
DC22554 |
MP-A08 |
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1). |
|
DC11856 |
MPC-0767 |
MPC-0767 (MPC0767, MPC3100 mesylate hydrate) is an L-alanine ester prodrug of MPC-3100, which is a potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM. |
|
DC22290 |
Aranidipine (MPC1304)
Featured
|
MPC1304 is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. IC50 & Target: Ca2+ Channel. |
|
DC7202 |
MPC-3100 |
MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. |
|
DC8339 |
MPEP hydrochloride
Featured
|
MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM. |
|
DC1015 |
MPEP
Featured
|
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM. |
|
DC20464 |
mPGES1-IN-16 |
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM. |
|
DC20465 |
mPGES1-IN-17d |
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM. |
|
DC11241 |
MP-HJ-1b |
MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation. |
|
DC10063 |
MPI-5a
Featured
|
MPI_5a is a potent selective inhibitor of HDAC6, and poorly blocks other HDAC enzymes. |
|
DC7470 |
MPI-0479605
Featured
|
MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases. |
|
DC8119 |
Mps1-IN-2
Featured
|
Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM. |
|
DC23974 |
Mps1-IN-3
Featured
|
Mps1-IN-3 is a selective and highly potent Mps1 kinase inhibitor with IC50 of 50 nM. |
|
DC10951 |
MPT0E028 |
MPT0E028 is a potent HDAC inhibitor that inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells, 9-30 times more potent than SAHA. |
|
DC10938 |
MPT0G211 |
MPT0G211 is a novel potent, selective HDAC6 inhibitor with IC50 of 0.291 nM, displays >1,000-fold selectivity over other HDAC isoforms. |
|
DC9542 |
MPTP (hydrochloride)
Featured
|
MPTP HCl induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats
|
|
DC10437 |
MRE-269
Featured
|
MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist. |
|
DC3122 |
MRK003 |
MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma. |
|
DC23877 |
MRK-560 |
MRK-560 is a potent, brain-penetrant and orally bioavailable γ-secretase inhibitor that inhibits proteolytic cleavage of APP over the Notch pathway. |
|
DC23655 |
MRK-623 |
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist.. |
|