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Cat. No.	Product Name	Field of Application
DC23616	MRK-696	MRK-696 is a non-selective benzodiazepine receptor partial agonist..
DC21923	MRK-A	MRK-A is a potent, highly selective, brain penetrant inhibitor of mutant IDH1 with IC50 of 5 nM, displays a 10,000-fold mutant to wildtype selectivity ratio.
DC21343	MRL-1237	MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
DC23711	MRL20	MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM.
DC11047	MRL871 Featured	MRL-871 (MRL871) is a potent, selective inhibitor of RORγt via allosteric inverse agonism, inhibits coactivator binding with IC50 of 7 nM; significantly reduces the IL17a mRNA levels in EL4 murine lymphoblast cell line at 10 uM.
DC20220	MRS-1845 Featured	MRS 1845 is a potent calcium channel protein inhibitor and inhibits capacitative Ca2+ influx in HL-60 cells (IC50 = 1.7 mM).
DC23483	MRS 2179	MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
DC23471	MRS 2179 tetrasodium	MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
DC23733	MRS 2481	MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.
DC23740	MRS 2485	MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..
DC12260	MRS1177	MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
DC12258	MRS1186	MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.
DC12251	MRS-1706 Featured	MRS-1706 is a potent and selective adenosine A2B receptor antagonist with Ki of 1.39 nM.
DC12803	MRS1754 Featured	MRS1754 is a selective adenosine A2B receptor antagonist (Ki values are 1.97, 16.8, 403, 503, 570 and 612 nM for hA2B, rA1, hA1, hA2A, hA3 and rA2A receptors respectively).
DC7203	MRS 2578 Featured	MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.
DC22164	MRS4458	MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors..
DC22165	MRS4478	MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors..
DC21344	MRT 199665	MRT 199665 is a potent salt-inducible kinases (SIKs) inhibitor with IC50 of 110, 12, 43 nM for SIK1,2,3 respectively.
DC10635	MRT67307 HCl Featured	MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.
DC23898	MRT-83 hydrochloride	MRT-83 hydrochloride is a potent Smoothened antagonist that blocks Hedgehog (Hh) signaling in various assays with IC50 of 10 nM.
DC12288	MRT-83	MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range.
DC12651	MRTX1257 Featured	MRTX1257 (MRTX-1257, MRTX 1257) is a potent, selective, covalent and irreversible inhibitor of KRAS G12C, inhibits KRAS dependent ERK-phosphorylation in the H358 cell with IC50 of 0.9 nM.
DC21346	MS012	MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..
DC21347	MS0124 Featured	MS-0124 is a potent and selective inhibitor of G9a-like Protein (GLP) lysine methyltransferase with IC50 of 13 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..
DC9293	MS023 Featured	MS023 is a potent, selective, and cell-active inhibitor of human type I PRMTs with IC50 of 4-119 nM.
DC8805	MS049 (hydrochloride) Featured	MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 that is active in cells.
DC21348	MS2734 Featured	MS2734 is a bisubstrate Nicotinamide N-methyltransferase (NNMT) with IC50 of 14 uM, Kd of 2.7 uM..
DC8574	MS37452 Featured	MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).
DC21349	MS-377	MS-377 is a potent, selective sigma-1 receptor ligand with Kd of 15.2 nM, showed anti-phencyclidine (PCP), anti-dopaminergic and anti-serotonergic activities.
DC22871	MS-402 Featured	MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice.

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