| DC11343 |
MMP-2/MMP-9 Inhibitor III |
MMP-2/MMP-9 inhibitor III is a cyclic peptide inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 10-20 μM for both). |
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| DC20039 |
MMP3 inhibitor 1 |
MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC50 of 1 nM. |
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| DC11355 |
MMP-3 Inhibitor
Featured
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MMP-3 inhibitor is a peptide inhibitor of matrix metalloproteinase-3 (MMP-3) with a Ki value of 95 nM. |
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| DC21332 |
MMPI-1154 |
MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively. |
|
| DC23313 |
MMRi6 |
MMRi6 is a small molecule inhibitor that disrupts Mdm2-MdmX RING-RING interaction interactions in vitro and activates p53 in cancer cells.. |
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| DC23279 |
MMRi64 |
MMRi64 is a small molecule inhibitor that disrupts Mdm2-MdmX RING-RING interaction interactions in vitro and activates p53 in cancer cells. |
|
| DC20461 |
MMSET-IN-1 |
MMSET-IN-1 is a potent, selective epigenetic oncogene MMSET (aka NSD2 or WHSC1) inhibitor with Ki/IC50 of 1.6/3.3 uM. |
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| DC21333 |
MMV390048
Featured
|
MMV390048 is a novel potent Plasmodium PI4K inhibitor with IC50 of 28 nM against intraerythrocytic life cycle stages of P. falciparum (NF54 drug-sensitive strain). |
|
| DC22654 |
MMV-667492
Featured
|
MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM. |
|
| DC7749 |
MN-001 (Tipelukast) |
MN-001 (tipelukast), a novel, orally bioavailable drug, reduces fibrosis and inflammation and down-regulates TIMP-1, collagen Type 1 and LOXL2 mRNA overexpression |
|
| DC21275 |
MN30 |
MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM. |
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| DC21335 |
MN58b
Featured
|
MN58b is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.4 uM, >30-fold selectivity over ChoKβ and does not affect MAPKs, PI3Ks, and other enzymes involved in the regulation of phospholipid metabolism. |
|
| DC8659 |
MN-64
Featured
|
MN-64 is a inhibitor of tankyrases, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition. |
|
| DC20463 |
MNK inhibitor 9 |
MNK inhibitor 9 is a potent, selective MAPK-interacting kinase (MNK1 and MNK2) inhibitor with IC50 of 3 nM for both, with no activity aginst CDK1/2 (IC50>25 uM). |
|
| DC21337 |
MNKI-19 |
MNKI-19 is a potent and dual-specific Mnk inhibitor with Ki of 186 nM and 68 nM for Mnk1 and Mnk2, respectively. |
|
| DC21338 |
MNKI-85 |
MNKI-85 is a potent and selective Mnk2 inhibitor with Ki of 31 nM, displays no inhibitory activities against Mnk1, CDK2A, CDK9T, and CDK4D. |
|
| DC21336 |
MNKI-8e |
MNKI-8e (MNK inhibitor 8e) is a potent, selective MNK inhibitor that inhibits Mnk2 with Ki of 0.37 uM, displays >34-fold and 4-fold over CDK2 (Ki>10 uM) and CDK9 (Ki=1.66 uM). |
|
| DC20462 |
MNK-IN-54 |
MNK-IN-54 is a potent, orally bioavailable dual MNK1/2 and BCR-ABL1 inhibitor with IC50 of 20/10/200/10 nM for Abl T315I/ wt Abl/MNK1/MNK2, respectively. |
|
| DC9326 |
Moexipril (hydrochloride) |
Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure. |
|
| DC12496 |
Mofezolac
Featured
|
Mofezolac is a Highly Selective Cyclooxygenase-1 Inhibitors,Counteracting Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation. |
|
| DCAPI1029 |
Moguisteine
Featured
|
Moguisteine is a novel peripheral non-narcotic antitussive drug. |
|
| DC9425 |
Molindone (hydrochloride) |
Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses. |
|
| DC22320 |
Mollugin
Featured
|
Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. |
|
| DC8991 |
Molsidomine |
Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound. |
|
| DCAPI1363 |
Mometasone furoate |
Mometasone furoate |
|
| DC2082 |
Monastrol
Featured
|
Monastrol is a reversible, cell-permeable inhibitor of the motor protein Eg5 (kinesin family protein 11, Kif11), blocking basal ATPase activity in vitro (IC50 = 6.1 µM) and inducing the formation of monoastral spindles in cell-based assays (IC50 = 51.3 μM |
|
| DCAPI1006 |
Monobenzone (Benoquin) |
Monobenzone (Benoquin) |
|
| DC7690 |
MMAD
Featured
|
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. |
|
| DC7685 |
MMAF
Featured
|
Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody drug cytotoxin. |
|
| DC20042 |
Monooctyl succinate |
Monooctyl succinate is a monoester, which can be used as a surfactants and a potential fragrance releaser. |
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