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Cat. No. Product Name Field of Application Chemical Structure
DC9318 Piboserod Featured Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.
DC10728 Pibrentasvir(ABT-530) Featured Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.
DC23700 Piclamilast Piclamilast (RP-73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM.
DC21511 Pico145 Pico145 is a highly potent, subtype-selective TRPC1/4/5 channels inhibitor with potency ranged from 9 to 1300 pM, depending on the TRPC1/4/5 subtype and activation mechanism.
DC7949 Picoxystrobin Picoxystrobin is an methoxyacrylate strobilurin fungicide designed for the control of wide range of cereal diseases.
DC8426 Picropodophyllin (PPP) Featured Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM.
DCAPI1426 Pidotimod Featured Pidotimod is a synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses. This compound has been shown to induce dendritic cell maturation and up-regulate the expression of HLA-DR and co-stimulatory molecu
DC9505 Pifithrin-α (hydrobromide) Featured Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes.
DC8144 Pifithrin-β (hydrobromide) Featured Pifithrin-β HBr (Cyclic Pifithrin-α HBr) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the human ovarian carcinoma cell line, IGROV-1.
DC7233 Pifithrin-u Featured Pifithrin-μ is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2, and also inhibits HSP70 function and autophagy.
DC9661 PIK-293 Featured PIK-293 is a PI3K inhibitor, mostly for PI3Kδ with IC50 of 0.24 μM, 500-, 100- and 50-fold less potent to PI3Kα/β/γ, respectively.
DC7234 PIK-294 Featured PIK-294 is a highly selective p110δ inhibitor with IC50 of 10 nM, 1000-, 49- and 16-fold less potent to PI3Kα/β/γ, respectively.
DC7235 PIK-75 Featured PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.
DC1096 PIK90 Featured PIK-90 is a potent and cell permeable inhibitor of p110α, p110β, p110γ and p110δ with IC50 of 11 nM, 350 nM, 18 nM and 58 nM, respectively.
DC8254 PIK-93 Featured PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM; shown to inhibit PI3Kα with IC50 of 39 nM.
DC9747 PIK-III Featured PIK-III, which is a selective inhibitor of ​VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates.
DC8184 Pilaralisib(XL-147; SAR245408) Featured Pilaralisib (SAR245408; XL147) is selective oral pan-PI3K inhibitor.
DCAPI1588 Pilsicainide hydrochloride Pilsicainide hydrochloride is a selective Na+ channel blocker (IC30 values are 9 and 60 μM for inward Na+ and Ca2+ currents respectively). Shows antiarrhythmic effects in vivo. Orally active.
DC21938 Pim inhibitor 28 Pim inhibitor 28 is a potent, selective inhibitor of Pim1/2 with IC50 of 0.05 nM for both, demonstrates on-target Pim activity in an in vivo pharmacodynamic assay with significant inhibition of BAD phosphorylation in KMS-12-BM multiple myeloma tumors..
DC9593 Pim1/AKK1-IN-1 Featured PIM/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively; also inhibits MPSK1 and TNIK.
DC10047 PIM-447 dihydrochloride Featured PIM447 is novel pan-PIM kinase inhibitor, including Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase.
DC8795 Pimavanserin(ACP-103) Featured Pimavanserin(ACP-103) is a potent and selective 5-HT2A receptor inverse agonist with mean pIC50 of with 8.7 in the cell-based functional assay.
DC8243 Pimecrolimus Featured Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12.
DC8661 Pimelic Diphenylamide 106(TC-H 106) Featured Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDAC (HDAC 1, 2, and 3, with IC50 values of 150 nM , 760nM, and 370 nM, respectively), demonstrating no activity against class II HDACs.
DC23557 Pim-IN-22m Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively.
DC7236 Pimobendan Featured Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
DC9815 Pimodivir(VX-787) Featured Pimodivir(VX-787) is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. 
DC20505 Pimozide Featured Pimozide is an antipsychotic agent that acts as an antagonist of the D2, D3, and D4 receptors and the 5-HT7 receptor, also is an inhbitor of STAT5.
DC12584 API-1 Pin1 inhibitor API-1 (API-1) is a potent, specific inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) and inhibits Pin1 cis-trans isomerizing activity with IC50 of 72.3 nM, displays remarkable selectivity over other peptidyl-prolyl
DC21939 PIN1 inhibitor VS10 PIN1 inhibitor VS10 is a novel potent small molecule inhibitor of PIN1 (peptidyl-prolyl cis-trans isomerase, NIMA-interacting 1), inhibits human PIN1 isomerization with IC50 of 13.4 uM, displays >2-fold more potency than ATRA.

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