Cat. No. | Product name | CAS No. |
DC23878 |
20(S)-Hydroxycholesterol
20(S)-Hydroxycholesterol is an allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein, binds at a site distinct from the canonical cyclopamine binding site. |
516-72-3 |
DC9647 |
20-Deoxyingenol
Featured
20-Deoxyingenol is a natural compound. |
54706-99-9 |
DC9655 |
20-O-Acetylingenol-3-angelate
Featured
20-O-Acetylingenol-3-angelate is a diterpene ester that has been found in E. peplus and a derivative of ingenol-3-angelate |
82425-35-2 |
DC23871 |
22-Azacholesterol
22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells.. |
3915-24-0 |
DC10666 |
MDK-7933
Featured
MDK-7933, also known as HDAC8-IN-1, is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). MDK-7933 was first reported in ChemMedChem. 2012 Oct;7(10):1815-24. MDK-7933 has CAS#1417997-93-3. |
1417997-93-3 |
DCAPI1409 |
Maxacalcitol
22-Oxacalcitriol is a Vitamin D3 analog which is Non-calcemic as well as a VDR ligand. 22-Oxacalcitriol has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro. Additionally has been noted to exhibit similar effects to calcitriol in |
103909-75-7 |
DC12367 |
Cyclic guanosine monophosphate-adenosine monophosphate
Featured
2'3'-cGAMP has been used to identify small compounds capable of binding human stimulator of interferon genes (STING). It is also used to study type I interferon response to cytosolic DNA. |
1441190-66-4 |
DC9802 |
23-hydroxy butulinic acid (23-HBA)
Featured
23-hydroxy butulinic acid (23-HBA) is a potent angiogenesis inhibitor. |
85999-40-2 |
DC12231 |
25-Hydroxycholesterol
Featured
25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50≈65 nM) and selective suppressor of IgA production by B cells. |
2140-46-7 |
DCAPI1508 |
25-OH-VD2
25-Hydroxyvitamin D2 is used in serum to measure the concentration of vitamin D produced by the skin. It is known that 25-Hydroxyvitamin D2 can be detected in human serum using high-performance liquid chromatography and ultraviolet detection. Vitamin D2, |
21343-40-8 |
DC20210 |
2-Aminoethanethiol;cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine
2-Aminoethanethiol (cysteamine) is a radiation-protective agent that oxidizes in air to form cystamine. |
60-23-1 |
DC22088 |
2BAct
Featured
2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays. |
2143542-28-1 |
DC20184 |
2-cyano-Pyrimidine
2-cyano-Pyrimidine is a cathepsin K inhibitor with an IC50 of 170 nM. |
14080-23-0 |
DC20158 |
2'-Deoxyadenosine monohydrate
Featured
2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis. |
16373-93-6 |
DC20144 |
2-Furoic acid
Featured
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats. |
88-14-2 |
DC20137 |
2'-Hydroxy-4'-methylacetophenone
Featured
2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. It could be used in the preparation of 4’-methyl-2’-[(p-tolylsulfonyl) oxy] acetophenone. |
6921-64-8 |
DC8952 |
Mesna
2-mercaptoethane sulfonate (Mesna), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide. |
19767-45-4 |
DC9044 |
2-Methoxyestradiol
Featured
2-methoxyestradiol (2ME2; NSC-659853) is a natural metabolite of estrogen that is known to inhibit HIF-1 alpha with an IC50 of 0.71 ± 0.11 μM for the inhibition of BPAEC migration. |
362-07-2 |
DC12356 |
2-NBDG
Featured
2-NBDG is a fluorescent indicator for direct glucose uptake measurement and also is an indicator of cell viability. |
186689-07-6 |
DC12293 |
2''-O-Rhamnosylicariside II
2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis. |
135293-13-9 |
DC8572 |
2-Phenyl-2-(1-piperidinyl)propane
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM). |
92321-29-4 |
DC20134 |
2-Phenylethanol
Featured
2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water. It has a pleasant floral odor and also an autoantibiotic produced by |
60-12-8 |