Cat. No. | Product name | CAS No. |
DC44873 |
Thalidomide-Piperazine-PEG3-NH2
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2357113-68-7 |
DC44874 |
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2435572-48-6 |
DC44875 |
Thalidomide-Propargyne-PEG1-COOH
Thalidomide-Propargyne-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44876 |
Thalidomide-5-PEG3-NH2
Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44877 |
Glutarimide-Isoindolinone-NH-PEG2-COOH
Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. |
|
DC44878 |
Thalidomide-Propargyne-PEG2-COOH
Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44879 |
Thalidomide-PEG3-COOH
Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44880 |
Thalidomide-5-PEG4-NH2
Thalidomide-5-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44881 |
Thalidomide-Piperazine-PEG1-COOH
Thalidomide-Piperazine-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44882 |
Glutarimide-Isoindolinone-NH-PEG3-COOH
Glutarimide-Isoindolinone-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. |
|
DC44883 |
Thalidomide-Propargyne-PEG3-COOH
Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44884 |
Thalidomide-PEG4-COOH
Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44885 |
Thalidomide-Piperazine-PEG2-COOH
Thalidomide-Piperazine-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44886 |
Glutarimide-Isoindolinone-NH-PEG4-COOH
Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. |
|
DC44887 |
Thalidomide-PEG5-COOH
Thalidomide-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44888 |
Thalidomide-Piperazine-PEG3-COOH
Thalidomide-Piperazine-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44889 |
Pomalidomide 4'-PEG3-azide
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach. |
2271036-46-3 |
DC44905 |
Vepdegestrant (ARV-471)
Featured
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer. |
2229711-68-4 |
DC45199 |
PROTAC BRD4 Degrader-10
PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively. |
2417370-49-9 |
DC45200 |
PROTAC BRD4 Degrader-12
PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively. |
2417370-90-0 |
DC45201 |
PROTAC BRD4 Degrader-13
PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively. |
2417370-71-7 |
DC45202 |
PROTAC BRD4 Degrader-11
PROTAC BRD4 Degrader-11 (compound 9a) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively. |