Cat. No. | Product name | CAS No. |
DC40603 |
Methyltetrazine-PEG4-amine hydrochloride
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC40604 |
Bromoacetamide-PEG3-C1-acid
Bromoacetamide-PEG3-C1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
173323-22-3 |
DC40605 |
Mal-amide-PEG2-oxyamine
Mal-amide-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2253965-09-0 |
DC40606 |
Methyltetrazine-PEG4-SSPy
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC40607 |
DBCO-C2-SulfoNHS ester
DBCO-C2-SulfoNHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1803279-86-8 |
DC40608 |
Bis-BCN-PEG1-diamide
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC40628 |
XZ739
XZ739, a CRBN-dependent PROTAC BCL-XL degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis. |
2365172-19-4 |
DC40722 |
PROTAC BRD4 Degrader-5-CO-PEG3-N3
PROTAC BRD4 Degrader-5-CO-PEG3-N3 (Compound 2) is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader GNE-987 and PEG-based linker. |
|
DC40723 |
PROTAC BRD4 Degrader-5
PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines. |
2409538-70-9 |
DC40737 |
Pomalidomide-C7-COOH
Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders. |
2225940-51-0 |
DC40786 |
(S,R,S)-AHPC-C6-NH2 hydrochloride
Featured
(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1. |
2360522-76-3 |
DC40834 |
Aldehyde-benzyl-PEG5-alkyne
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1378928-83-6 |
DC40840 |
6-Maleimidocaproic acid sulfo-NHS
6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
103848-61-9 |
DC40841 |
3-Mercaptopropionic acid NHS ester
Featured
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
117235-10-6 |
DC40842 |
Mal-amino-sulfo
Mal-amino-sulfo is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
158018-81-6 |
DC40843 |
(S,R,S)-AHPC-C7-amine
(S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. |
2306389-04-6 |
DC40844 |
(S,R,S)-AHPC-C5-NH2
(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. |
2170695-19-7 |
DC40858 |
BSJ-04-132
BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader (PROTAC), with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity. |
2349356-39-2 |
DC40864 |
A 410099.1, amine-Boc hydrochloride
A 410099.1, amine-Boc hydrochloride is a?functionalized IAP ligand for PROTACs. that is incorporates with an amine functional handle for ready conjugation to a linker/target protein ligand. |
2374122-37-7 |
DC40865 |
A 410099.1 amide-PEG3-amine-Boc
A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG3-amine-Boc can conjugates with target protein ligands. |
2415256-19-6 |
DC40866 |
A 410099.1 amide-PEG2-amine-Boc
A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG2-amine-Boc can conjugates with target protein ligands. |
2415256-16-3 |
DC40867 |
Boc-A 410099.1 amide-alkylC4-amine
Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-alkylC4 linker with terminal amine. Boc-A 410099.1 amide-alkylC4-amine can conjugates with target protein ligands. |
2415256-18-5 |