| DC40592 |
Folate-PEG1-mal |
Folate-PEG1-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40593 |
Folate-PEG2-amine |
Folate-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40594 |
Folate-PEG3-alkyne |
Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40595 |
HyNic-PEG2-TCO |
HyNic-PEG2-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40596 |
HyNic-PEG2-DBCO |
HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40597 |
Boc-HyNic-PEG1-mal |
Boc-HyNic-PEG1-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40598 |
Boc-HyNic-PEG2-alkyne |
Boc-HyNic-PEG2-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40599 |
Boc-HyNic-PEG2-N3 |
Boc-HyNic-PEG2-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40600 |
Boc-HyNic-PEG2-DBCO |
Boc-HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40601 |
Mal-amide-PEG2-oxyamine-Boc |
Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40603 |
Methyltetrazine-PEG4-amine hydrochloride |
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40604 |
Bromoacetamide-PEG3-C1-acid |
Bromoacetamide-PEG3-C1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40605 |
Mal-amide-PEG2-oxyamine |
Mal-amide-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40606 |
Methyltetrazine-PEG4-SSPy |
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40607 |
DBCO-C2-SulfoNHS ester |
DBCO-C2-SulfoNHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40608 |
Bis-BCN-PEG1-diamide |
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40628 |
XZ739 |
XZ739, a CRBN-dependent PROTAC BCL-XL degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis. |
|
| DC40722 |
PROTAC BRD4 Degrader-5-CO-PEG3-N3 |
PROTAC BRD4 Degrader-5-CO-PEG3-N3 (Compound 2) is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader GNE-987 and PEG-based linker. |
|
| DC40723 |
PROTAC BRD4 Degrader-5 |
PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines. |
|
| DC40737 |
Pomalidomide-C7-COOH |
Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders. |
|
| DC40786 |
(S,R,S)-AHPC-C6-NH2 hydrochloride
Featured
|
(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1. |
|
| DC40834 |
Aldehyde-benzyl-PEG5-alkyne |
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40840 |
6-Maleimidocaproic acid sulfo-NHS |
6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40841 |
3-Mercaptopropionic acid NHS ester
Featured
|
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40842 |
Mal-amino-sulfo |
Mal-amino-sulfo is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC40843 |
(S,R,S)-AHPC-C7-amine |
(S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. |
|
| DC40844 |
(S,R,S)-AHPC-C5-NH2 |
(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader. |
|
| DC40858 |
BSJ-04-132 |
BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader (PROTAC), with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity. |
|
| DC40864 |
A 410099.1, amine-Boc hydrochloride |
A 410099.1, amine-Boc hydrochloride is a?functionalized IAP ligand for PROTACs. that is incorporates with an amine functional handle for ready conjugation to a linker/target protein ligand. |
|
| DC40865 |
A 410099.1 amide-PEG3-amine-Boc |
A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG3-amine-Boc can conjugates with target protein ligands. |
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