Cat. No. | Product name | CAS No. |
DC7992 |
PX 12
Featured
PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
141400-58-0 |
DCAPI1165 |
Ribavirin (Copegus)
Featured
Ribavirin is a guanosine analog with antiviral properties against DNA and RNA viruses, including respiratory syncytial virus, hepatitis C, and influenza. |
36791-04-5 |
DC9475 |
Ritonavir
Featured
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS,showed potent activity against COVID-19(SARS-COV-2) . |
155213-67-5 |
DC5105 |
Favipiravir (T-705)
Featured
T 705(Favipiravir) is a RNA-directed RNA polymerase NS5B inhibitor.T 705(Favipiravir) is useful for Antiviral agents. |
259793-96-9 |
DC9180 |
Tamoxifen Citrate
Featured
Tamoxifen(ICI-46474) is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(10.117), SARS-COV(11.696). |
54965-24-1 |
DC2067 |
TDZD-8
Featured
TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM. |
327036-89-5 |
DC1008 |
Telaprevir (VX-950)
Featured
Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM. |
402957-28-2 |
DC21567 |
Triazavirin (Riamilovir)
Featured
Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain. It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications.5 Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19. |
928659-17-0 |
DCAPI1063 |
Zanamivir (Relenza)
Featured
Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively. |
139110-80-8 |
DC10325 |
Aviptadil
Featured
Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction,showed potent activity against COVID-19(SARS-COV-2). |
40077-57-4 |
DC26121 |
FOY-251 mesylate
Featured
FOY 251 is a metabolite of Camostat and a pollen protease inhibitor for prevention and control of allergy. |
71079-09-9 |
DC26133 |
Camostat mesylate
Featured
Camostat mesylate is a synthetic, orally bioavailable is a serine protease inhibitor. Used for the treatment of chronic pancreatitis. It attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. |
59721-29-8 |
DC11735 |
Remdesivir(GS-5734)
Featured
Remdesivir is a novel RNA-dependent RNA Polymerase,(RdRp) inhibitor. The purity of remdesivir>99.8%,signal impurity<0.05%. |
1809249-37-3 |
DC26208 |
Remdesivir metabolite(GS-441524)
Featured
Remdesivir metabolite.Remdesivir blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 Nm,and also showed potent activity blocking 2019-nCov(Coronavirus). |
1191237-69-0 |
DC26230 |
Furin Inhibitor I
Featured
Furin inhibitor I is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LP |
150113-99-8 |
DC26232 |
DX 600(ACE2 Inhibitor)
Featured
DX600 is a potent and selective peptide inhibitor of angiotensin-converting enzyme 2 (ACE2; Kis = 2.8, 200, and 1,200 nM for recombinant, human, and murine ACE2, respectively). |
478188-26-0 |
DC26231 |
Furin Inhibitor II(Hexa-D-arginine)
Featured
Inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively). |
673202-67-0 |
DC27020 |
Arbidol analog
Featured
A Arbidol analog which showed affinity against both H3 (1150-fold) and H1 (98-fold) hemagglutinin subtypes than Arbidol. |
2126032-35-5 |
DC27035 |
EIDD-2801(Molnupiravir)
Featured
Molnupiravir, also known as EIDD-2801 and MK-4482, is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of multiple RNA viruses including SARS-CoV-2, the causative agent of COVID-19. EIDD-2801 has been show |
2492423-29-5 |
DC28010 |
Carolacton
Carolacton is a novel MTHFD1 inhibitor,an antibacterial compound,also showed potent activity against COVID-19(SARS-COV-2). |
476645-77-9 |
DC28040 |
SBP1(spike-binding peptide 1)
Featured
SBP1(spike-binding peptide 1) is a first-in-class peptide binder to the SARS-CoV-2 spike protein. SBP1 specifically binds SARS-CoV-2-RBD with low nanomolar affinity. SBP1 to the RBD was determined to be 47 nM with the average Kon = 4.69*104M-1S-1 and Koff |
|
DC28041 |
BIOTIN-PEG4-SBP1(spike-binding peptide 1)
Featured
Biotin modification of SBP1.SBP1(spike-binding peptide 1) is a first-in-class peptide binder to the SARS-CoV-2 spike protein. SBP1 specifically binds SARS-CoV-2-RBD with low nanomolar affinity. SBP1 to the RBD was determined to be 47 nM with the average Kon = 4.69*104M-1S-1 and Koff=2.2*10-3.The interaction between SBP1 and the RBD of SARS-CoV-2 spike protein was validated by bio-layer interferometry. The KD, derived from protein association and dissociation kinetics, was found to be 47 nM after averaging the fitting values at different protein concentrations. The amino acid sequence of SBP1 is entirely derived from human ACE2 and should be recognized as endogenous by the human immune system. This feature could be highly beneficial in later stages of pre-clinical development. |