D609

  Cat. No.:  DC9589   Featured
Chemical Structure
83373-60-8
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More than 5000 active chemicals with high quality for research!
Field of application
D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent.
Cas No.: 83373-60-8
Chemical Name: Carbonodithioic acid,O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1)
Synonyms: Carbonodithioic acid,O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1);D609;Carbonodithioic Acid O-(Octahydro-4,7-methano-1H-inden-5-yl) Ester Potassium Salt;D609 (potassium salt);D609,O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonopotassiumdithioate;D609,POTASSIUM SALT (Tricyclodecan-9-yl-xanthogenate, K );D-609;D-609 POTASSIUM;D609 POTASSIUM SALT;Tricyclodecan-9-yl xanthate;Tricyclodecan-9-yl xanthate potassium salt;Tricyclodecan-9-yl xanthogenate;TRICYCLODECAN-9-YL XANTHOGENATE K;tricyclodecane-9-yl-xanthogenate;Potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate
SMILES: [K].SC(=S)OC1C2C3C(CCC3)C(C1)C2
Formula: C11H16Os2.K
M.Wt: 267.47244
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: D609 is a selective competitive inhibitor of phosphatidyl choline-specific phospholipase C (PC-PLC), with Ki of 6.4 μM.
Target: Ki: 6.4 μM (PC-PLC)
References: [1]. Kalluri HS, et al. D609 inhibits the proliferation of neural progenitor cells.Neuroreport. 2010 Jul 14;21(10):700-3. [2]. Milhas D, et al. The Tricyclodecan-9-yl-xanthogenate D609 Triggers Ceramide Increase and Enhances FasL-Induced Caspase-Dependent and -Independent Cell Death in T Lymphocytes.Int J Mol Sci. 2012;13(7):8834-52. Epub 2012 Jul 16. [3]. Gusain A, et al. Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibition.Mol Neurobiol. 2012 Jun;45(3):455-64. Epub 2012 Mar 14.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
Cat. No. Product name Field of application
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DC9589 D609 D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent.
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