Cas No.: | 83373-60-8 |
Chemical Name: | Carbonodithioic acid,O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1) |
Synonyms: | Carbonodithioic acid,O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1);D609;Carbonodithioic Acid O-(Octahydro-4,7-methano-1H-inden-5-yl) Ester Potassium Salt;D609 (potassium salt);D609,O-(Octahydro-4,7-methano-1H-inden-5-yl)carbonopotassiumdithioate;D609,POTASSIUM SALT (Tricyclodecan-9-yl-xanthogenate, K );D-609;D-609 POTASSIUM;D609 POTASSIUM SALT;Tricyclodecan-9-yl xanthate;Tricyclodecan-9-yl xanthate potassium salt;Tricyclodecan-9-yl xanthogenate;TRICYCLODECAN-9-YL XANTHOGENATE K;tricyclodecane-9-yl-xanthogenate;Potassium O-(octahydro-4,7-methano-1H-inden-5-yl) dithiocarbonate |
SMILES: | [K].SC(=S)OC1C2C3C(CCC3)C(C1)C2 |
Formula: | C11H16Os2.K |
M.Wt: | 267.47244 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | D609 is a selective competitive inhibitor of phosphatidyl choline-specific phospholipase C (PC-PLC), with Ki of 6.4 μM. |
Target: | Ki: 6.4 μM (PC-PLC) |
References: | [1]. Kalluri HS, et al. D609 inhibits the proliferation of neural progenitor cells.Neuroreport. 2010 Jul 14;21(10):700-3. [2]. Milhas D, et al. The Tricyclodecan-9-yl-xanthogenate D609 Triggers Ceramide Increase and Enhances FasL-Induced Caspase-Dependent and -Independent Cell Death in T Lymphocytes.Int J Mol Sci. 2012;13(7):8834-52. Epub 2012 Jul 16. [3]. Gusain A, et al. Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibition.Mol Neurobiol. 2012 Jun;45(3):455-64. Epub 2012 Mar 14. |