Alternate Text DC Chemicals' products qualify for U.S. tariff exemptions. We guarantee no price increases due to customs duties and maintain stable supply, continuing to deliver reliable research solutions to our American clients.
Home > Products > Novel inhibitors

Trans-4-Phenyl-3-buten-2-one

  Cat. No.:  DC45583   Featured
Chemical Structure
1896-62-4
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86-021-58447131
Get Quotation Now
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
Trans-4-Phenyl-3-buten-2-one (trans-Benzylideneacetone, trans-Benzalacetone, trans-Benzylideneacetone) is an inhibitor of the enzyme phospholipase A2 (PLA2). Trans-4-Phenyl-3-buten-2-one is used as a flavouring agent, a fragrance and a bacterial metabolite.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1896-62-4
Chemical Name: (E)-4-Phenylbut-3-en-2-one
Synonyms: (E)-4-Phenylbut-3-en-2-one;(E)-1-Buten-3-one, 1-phenyl;(e)-3-buten-2-on;Methyl trans-styryl ketone;Tpbo;trans-4-phenyl-but-3-en-2-one;trans-Benzylidenacetone;FEMA 2881;(E)-4-Phenyl-3-buten-2-one;BAR;benzylidene acetone;trans-4-Phenyl-3-but;trans-4-Phenyl-3-buten-2-one;trans-Benzalacetone;2',4',6'-trimethyl-chalcone;2',4',6'-Trimethyl-chalkon;ANILINE,N-BENZYLIDENE-m-NITRO;Benzal-3-nitroaniline;benzalacetomesitylene;Benzal-m-nitroaniline;benzylidene-2,4,6-trimethylacetophenone;mesityl styryl ketone;N-Benzyliden-3-nitro-ani;N-benzylidene-3-nitro-aniline;N-Benzylidene-m-nitroaniline;TC-BAR;WLN: WNR CNU1R;trans-Benzylideneacetone;Methyl trans-Styryl Ketone;BENZALAOETONE;ACETOCINNAMONE;BENZYLIDENACETONE;TRANS-BENZALACETONE;CINNAMYL METHYL KETONE;1-PHENYL-1-BUTEN-3-ONE
SMILES: CC(C=CC1C=CC=CC=1)=O
Formula: C10H10O
M.Wt: 146.185802936554
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant[1].
Target: PLA2
In Vitro: Benzylideneacetone (trans-Benzylideneacetone; 0.005, 0.05, 0.5, 5, 50, 500, 5000 μM) inhibits hemocytespreading behavior of hemocytes of S. exigua larvae. Benzylideneacetone enhances virulence of Bacillus thuringiensisagainst beet armyworm[1].
References: [1]. Kwon B, et al. Benzylideneacetone, an immunosuppressant, enhances virulence of Bacillus thuringiensisagainst beet armyworm (Lepidoptera: Noctuidae). J Econ Entomol. 2008 Feb;101(1):36-41.
MSDS
TITLE DOWNLOAD
MSDS_29310_DC45583
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC71386 (2E)-OBAA (2E)-OBAA is a potent phospholipase A2 (PLA2) inhibitor, with an IC50 of 70 nM. (2E)-OBAA induces apoptosis of HUVEC cells. (2E)-OBAA blocks Melittin-induced Ca2+ influx in Trypanosoma brucei, with an IC50 of 0.4 μM.
DC70891 VU0285655-1 VU0285655-1 is a potent, selective inhibitor of PLD2, induces autophagy in colorectal cancer cells
DC45583 Trans-4-Phenyl-3-buten-2-one Trans-4-Phenyl-3-buten-2-one (trans-Benzylideneacetone, trans-Benzalacetone, trans-Benzylideneacetone) is an inhibitor of the enzyme phospholipase A2 (PLA2). Trans-4-Phenyl-3-buten-2-one is used as a flavouring agent, a fragrance and a bacterial metabolite.
DC43940 Melittin Melittin (MLT, Forapin, Forapine) is an activator of phospholipase A2 (PLA2) that stimulates the activity of the low molecular weight PLA2, while it does not the increase the activity of the high molecular weight enzyme.
DC28606 MJ33 MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6. MJ33 has a critical effect on inflammatory brain damage.
DC28393 Halopemide Halopemide is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent.
DC7966 U73122 U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase).
DC9589 D609 D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent.
X
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Site Map|Privacy PolicyCopyright © 2018-2020 All Rights Reserved. Technical Support:KuuJia