Cridanimod

Cas No.:	38609-97-1
Chemical Name:	Cridanimod
Synonyms:	9-Oxo-10(9H)-acridineacetic acid;10-carboxymethyl-9-acridanone;9-oxo-10(9h)-acridineaceticaci;(9 10-DIHYDRO-9-OXO-10-ACRIDINYL)ACETIC;acridin-9(10H)-one-n-acetic acid;ACRIDONE ACETIC ACID;(9-Oxo-10(9H)-acridinyl)acetic acid;10-Carboxymethylacridin-9(10H)-one;9-Oxoacridine-10-acetic Acid;(9-Oxo-9H-acridin-10-yl)-acetic acid;(9-oxoacridin-10(9H)-yl)acetic acid;10(9H)-ACRIDINEACETIC ACID, 9-OXO-;10-Carboxymeth-9-acridanone;10-carboxymethyl-9-acridinone;10-carboxymethyl-9-acridone;2-(9-oxo-9,10-dihydro-10-acridinyl)acetic acid;9,10-dihydro-9-oxo-10-acridineacetic acid;9-acridone-N-acetic acid;Acridone-N-acetic acid;BRN 0227508;Cridanimod;Cridanimod [INN];N-(Carboxymethyl)acridone;(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid;10-(Carboxymethyl)-9(10H)acridone;10-(Carboxymethyl)-9(10H)-acridone;Cycloferon;X91E9EME19;C15H11NO3;Cridanimod (INN);10(9H)-Acridineaceticacid, 9-oxo-;DSST
SMILES:	O=C1C2=C([H])C([H])=C([H])C([H])=C2N(C([H])([H])C(=O)O[H])C2=C([H])C([H])=C([H])C([H])=C21
Formula:	C15H11NO3
M.Wt:	253.2527
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Cridanimod is a small-molecule immunomodulator and interferon inducer[1]. Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression[2].
In Vivo:	Cridanimod (IM; 1-6 mg; twice a week) has a significantly longer survival time. Cridanimod significant increases in IFNα and -β in cridanimod-treated mice in a dose-dependent manner[1]. Animal Model: Athymic mice with hec50co cells[1] Dosage: 1, 3, 6 mg Administration: IM; twice a week Result: Had a significantly longer survival time.