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Cridanimod

  Cat. No.:  DC11641   Featured
Chemical Structure
38609-97-1
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More than 5000 active chemicals with high quality for research!
Field of application
A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
Cas No.: 38609-97-1
Chemical Name: Cridanimod
Synonyms: 9-Oxo-10(9H)-acridineacetic acid;10-carboxymethyl-9-acridanone;9-oxo-10(9h)-acridineaceticaci;(9 10-DIHYDRO-9-OXO-10-ACRIDINYL)ACETIC;acridin-9(10H)-one-n-acetic acid;ACRIDONE ACETIC ACID;(9-Oxo-10(9H)-acridinyl)acetic acid;10-Carboxymethylacridin-9(10H)-one;9-Oxoacridine-10-acetic Acid;(9-Oxo-9H-acridin-10-yl)-acetic acid;(9-oxoacridin-10(9H)-yl)acetic acid;10(9H)-ACRIDINEACETIC ACID, 9-OXO-;10-Carboxymeth-9-acridanone;10-carboxymethyl-9-acridinone;10-carboxymethyl-9-acridone;2-(9-oxo-9,10-dihydro-10-acridinyl)acetic acid;9,10-dihydro-9-oxo-10-acridineacetic acid;9-acridone-N-acetic acid;Acridone-N-acetic acid;BRN 0227508;Cridanimod;Cridanimod [INN];N-(Carboxymethyl)acridone;(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid;10-(Carboxymethyl)-9(10H)acridone;10-(Carboxymethyl)-9(10H)-acridone;Cycloferon;X91E9EME19;C15H11NO3;Cridanimod (INN);10(9H)-Acridineaceticacid, 9-oxo-;DSST
SMILES: O=C1C2=C([H])C([H])=C([H])C([H])=C2N(C([H])([H])C(=O)O[H])C2=C([H])C([H])=C([H])C([H])=C21
Formula: C15H11NO3
M.Wt: 253.2527
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Cridanimod is a small-molecule immunomodulator and interferon inducer[1]. Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression[2].
In Vivo: Cridanimod (IM; 1-6 mg; twice a week) has a significantly longer survival time. Cridanimod significant increases in IFNα and -β in cridanimod-treated mice in a dose-dependent manner[1]. Animal Model: Athymic mice with hec50co cells[1] Dosage: 1, 3, 6 mg Administration: IM; twice a week Result: Had a significantly longer survival time.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC11642 Cridanimod sodium Cridanimod sodium is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
DC11641 Cridanimod A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
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