Cas No.: | 916603-07-1 |
SMILES: | C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN |
Formula: | C17H16FN5 |
M.Wt: | 309.34 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Dianilinopyrimidine_01(CZC8004) is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase. |
References: | [1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC50 values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44. |