| DC72777 |
DS-9300
|
DS-9300 is a potent, orally active, selective EP300/CBP HAT inhibitor with an IC50 value of 28 nM. DS-9300 has anticancer activity and can be used in prostate cancer disease research. |
| DC40724 |
MS117
|
MS117 is a first-in-class and cell-active irreversible protein arginine methyltransferase 6 (PRMT6) covalent inhibitor, with an IC50 of 18 nM. |
| DC12370 |
YF2
|
YF2 is a First-in-Class Histone Acetyltransferase (HAT) Activators for Precision Targeting of Epigenetic Derangements in Lymphoma. |
| DC10880 |
WM-8014
|
WM-8014(WM8014) is a highly potent, selective inhibitors of KAT6A and KAT6B. |
| DC10881 |
WM-1119
|
WM-1119(WM1119) is a highly potent, selective inhibitors of KAT6A and KAT6B. |
| DC7794 |
MG149
|
MG 149 is an inhibitor of histone acetyltransferases (HAT) with IC50 values of 74μM and 47μM for Tip60 and MOF, respectively. |
| DC8578 |
L002(NSC764414)
|
L002 is a p300 inhibitor (IC50=1.98 μM) that inhibits p53 and histone acetylation. Suppresses STAT3 activation in vitro and suppresses tumor growth in some mouse cell lines. |
| DC9982 |
I-CBP112
|
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors CREBBP (CBP) and EP300 (IC50 = 0.142 and 0.625 μM, respectively). |
| DC7658 |
C646
|
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases. |
| DC8322 |
Anacardic Acid
|
Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (pCAF) with IC50 values of 8.5 and 5 µM, respectively. |
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