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IL-17 modulator 3

  Cat. No.:  DC46172   Featured
Chemical Structure
2467731-88-8
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More than 5000 active chemicals with high quality for research!
Field of application
IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2467731-88-8
Chemical Name: IL-17 modulator 3
Synonyms: 1H-Pyrazole-5-carboxamide, N-[(1S)-1-cycloheptyl-2-[[4-[(2R)-3-(4-methyl-1-piperazinyl)-3-oxo-2-[(1-oxopropyl)amino]propyl]phenyl]amino]-2-oxoethyl]-1-methyl-;1-methyl-pyrazole-5-carboxamide derivative;N-[(2R)-3-{4-[(2S)-2-cycloheptyl-2-[(1-methyl-1H-pyrazol-5-yl)formamido]acetamido]phenyl}-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl]propanamide;N-((S)-1-cycloheptyl-2-((4-((R)-3-(4-methylpiperazin-1-yl)-3-oxo-2-propionamidopropyl)phenyl)amino)-2-oxoethyl)-1-methyl-1H-pyrazole-5-carboxamide;IL-17 modulator 3
SMILES: N1(C)C(C(N[C@@H](C2CCCCCC2)C(NC2=CC=C(C[C@@H](NC(=O)CC)C(N3CCN(C)CC3)=O)C=C2)=O)=O)=CC=N1
Formula: C31H45N7O4
M.Wt: 579.73
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_29965_DC46172_2467731-88-8
COA
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Cat. No. Product name Field of application
DC72265 GDC-2394 GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation.
DC47194 IL-4-inhibitor-1 IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM.
DC46954 CVN03650(IL-17 modulator 4) IL-17 modulator 4 is a prodrug of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
DC46172 IL-17 modulator 3 IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
DC46037 LY3509754（IL-17A inhibitor 1） IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells.
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