IL-4-inhibitor-1|CAS 1332184-63-0|DC Chemicals

Cas No.:	1332184-63-0
Chemical Name:	IL-4-inhibitor-1
Synonyms:	2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)-3-pyridinecarbonitrile;2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)nicotinonitrile;2-AMINO-4-(3,4-DIHYDROXYPHENYL)-6-(4-FLUOROPHENYL)PYRIDINE-3-CARBONITRILE;IL-4-inhibitor-1;CHEMBL5266734;CS-0179575;SCHEMBL23833502;HY-139092;IL-4 Inhibitor;MS-24745;AKOS040755315;DA-74436;G14072;1332184-63-0;BDBM50409058
SMILES:	FC1C=CC(=CC=1)C1C=C(C(C#N)=C(N)N=1)C1C=CC(=C(C=1)O)O
Formula:	C₁₈H₁₂FN₃O₂
M.Wt:	321.305187225342
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

Cat. No.	Product name	Field of application
DC72265	GDC-2394	GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation.
DC47194	IL-4-inhibitor-1	IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM.
DC46954	CVN03650(IL-17 modulator 4)	IL-17 modulator 4 is a prodrug of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
DC46172	IL-17 modulator 3	IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
DC46037	LY3509754（IL-17A inhibitor 1）	IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells.