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LY3509754（IL-17A inhibitor 1）

  Cat. No.:  DC46037   Featured
Chemical Structure
2452464-73-0
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More than 5000 active chemicals with high quality for research!
Field of application
IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2452464-73-0
Chemical Name: IL-17A INHIBITOR 1
Synonyms: 1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-;LY-3533028;IL-17A inhibitor 1
SMILES: O1N=C(C)C(C(N[C@@H](C2CCC(F)(F)CC2)C2=CN3C(=N2)C=C([C@H](N2C(=O)N[C@H](C(F)(F)F)C2)COC)C=N3)=O)=N1
Formula: C24H27F5N8O4
M.Wt: 586.51
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC46954 CVN03650(IL-17 modulator 4) IL-17 modulator 4 is a prodrug of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
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DC46037 LY3509754（IL-17A inhibitor 1） IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells.
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