CVN03650(IL-17 modulator 4)

  Cat. No.:  DC46954   Featured
Chemical Structure
2446803-65-0
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More than 5000 active chemicals with high quality for research!
Field of application
IL-17 modulator 4 is a prodrug of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
Cas No.: 2446803-65-0
Chemical Name: 1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-
Synonyms: 1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-;IL-17 modulator 4
SMILES: N1(C(C)C)C(C(N[C@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C2CC2)C2CC2)=O)=CC=N1
Formula: C27H34N6O2
M.Wt: 474.60
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
Cat. No. Product name Field of application
DC72265 GDC-2394 GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation.
DC47194 IL-4-inhibitor-1 IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM.
DC46954 CVN03650(IL-17 modulator 4) IL-17 modulator 4 is a prodrug of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
DC46172 IL-17 modulator 3 IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
DC46037 LY3509754(IL-17A inhibitor 1) IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells.
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