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ADCs Linker/Click Chemistry

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Cat. No. Product Name Field of Application Chemical Structure
DC8703 Fmoc-Val-Cit-PAB Featured Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).
DC8701 Fmoc-Val-Cit-PAB-PNP Featured Fmoc-Val-Cit-PAB-PNP is a peptide prodrug linker, is a linker for antibody-drug-conjugation (ADC).
DC8461 Mc-Val-Cit-PABC-PNP(VCMMAE linker) Featured Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker.
DC28112 Propargyl-PEG4-C2-acid Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3.
DC28281 DBCO-NHCO-PEG4-NHS ester DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28293 Bis-PEG2-PFP ester Bis-PEG2-PFP ester is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bis-PEG2-PFP ester is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC28294 Bis-PEG1-PFP ester Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28350 Amino-PEG5-C2-acid Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28357 m-PEG5-Ms m-PEG5-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28368 m-PEG8-Ms m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28369 PEG12-Tos Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28371 N-Boc-N-bis(PEG2-OH) N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28372 Hydroxy-PEG4-acid Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28391 Propargyl-PEG2-acid Featured Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28406 m-PEG7-Amine m-PEG7-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28407 Tr-PEG3-OH Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28412 m-PEG5-CH2COOH Featured m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28413 N-Boc-PEG5-bromide N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28415 Amino-PEG10-OH Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28416 DBCO-PEG4-Maleimide DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28417 Boc-NH-PEG1-CH2CH2COOH Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs.
DC28418 Tr-PEG5-OH Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28444 DBCO-Sulfo-NHS ester sodium DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28451 Aminooxy-PEG4-alcohol Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC28464 DBCO-NHCO-PEG4-acid DBCO-Amide-PEG5-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC28484 PEG4-SPDP PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
DC28485 LC-PEG8-SPDP Featured LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
DC28486 PDEC-NB PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
DC28487 Propargyl-C1-NHS ester Propargyl-C1-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
DC28488 Propargyl-C2-NHS ester Propargyl-C2-NHS ester is a nonclaevable linker for antibody-drug-conjugation (ADC).
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