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3′,4′,5′,5,6,7-Hexamethoxyflavone

  Cat. No.:  DC45435  
Chemical Structure
29043-07-0
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More than 5000 active chemicals with high quality for research!
Field of application
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 29043-07-0
Chemical Name: 3′,4′,5′,5,6,7-Hexamethoxyflavone
SMILES: O=C1C=C(C2=CC(OC)=C(OC)C(OC)=C2)OC3=CC(OC)=C(OC)C(OC)=C13
Formula: C21H22O8
M.Wt: 402.39
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47407 Antimalarial agent 3 Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.
DC47406 Antileishmanial agent-2 Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
DC47405 Antimalarial agent 2 Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile.
DC47404 TCMDC-125431 TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
DC47403 TCMDC-136230 TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
DC47402 TCMDC-125457 TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
DC47401 Antileishmanial agent-1 Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM).
DC47400 BRD5018 BRD5018 is an antimalarial agent.
DC47399 MMV674850 MMV674850 is potent against asexual stage parasites at 2.7 and 4.5 nM and preferentially targets early-stage gametocytes (early-stage gametocyte: IC50 4.5 ± 3.6 nM; late-stage gametocyte: IC50 28.7 ± 0.2 nM).
DC47398 MMV666810 MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM).
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