Cat. No. | Product name | CAS No. |
DC5177 |
Nepicastat HCl (SYN-117)
Featured
Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. |
170151-24-3 |
DC9796 |
Nicainoprolhe(Nicainoprol)
Featured
Nicainoprolhe is an antiarrhythmic agent,a fast-sodiumchannel blocking drug (class Ib), also protected isolated rat hearts against reperfusion arrhythmias. |
76252-06-7 |
DC9170 |
Nicardipine hydrochloride
Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. |
54527-84-3 |
DC9108 |
Nisoldipine
Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
63675-72-9 |
DC10134 |
Obicetrapib (AMG-899,TA-8995)
Featured
Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy. |
866399-87-3 |
DCAPI1464 |
Olmesartan
Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction. |
144689-24-7 |
DC9179 |
Olmesartan MedoxoMil
Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive. |
144689-63-4 |
DC10324 |
Omapatrilat
Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with Ki values of 0.64 and 0.45 nM, respectively. |
167305-00-2 |
DC9443 |
Otamixaban
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. |
193153-04-7 |
DC7970 |
ACT058362 (Palosuran)
Featured
Palosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM. |
540769-28-6 |
DC7224 |
PD 123319
Featured
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. |
136676-91-0 |
DC11360 |
Pemafibrate
Featured
Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis. |
848259-27-8 |
DC10500 |
PF-06282999
Featured
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases. |
1435467-37-0 |
DC10012 |
Pirmenol hydrochloride
Featured
Pirmenol hydrochloride inhibits IK.ACh by blocking muscarinic receptors. The IC50 of Pirmenol for inhibition of Carbachol-induced IK.ACh is 0.1 μM. |
61477-94-9 |
DC6903 |
Lapaquistat Acetate (TAK-475)
Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs. |
189060-13-7 |
DC11138 |
Guanabenz acetate
R15A inhibitor. |
23256-50-0 |
DC5108 |
BAY 59-7939 (Rivaroxaban)
Featured
Rivaroxaban (Xarelto; BAY 59-7939) is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. |
366789-02-8 |
DC9666 |
Ro 46-2005
Featured
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM. |
150725-87-4 |
DC7933 |
Ro 48-8071 fumarate
Featured
Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity. |
189197-69-1 |
DC7490 |
Rostafuroxin
Featured
Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension. |
156722-18-8 |
DC9313 |
Sarpogrelate (hydrochloride)
Featured
Sarpogrelate(MCI-9042) hydrochloride, a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. |
135159-51-2 |
DC10700 |
Seladelpar
Featured
Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist. |
851528-79-5 |