| DC10386 |
Tenapanor
Featured
|
Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively. |
|
| DC9609 |
Terutroban
Featured
|
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
|
|
| DC1101 |
Ticagrelor (Brilinta,AZD6140)
Featured
|
Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist, also inhibits CYP2C9 and 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively. |
|
| DC9489 |
Tirofiban (hydrochloride monohydrate)
Featured
|
Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist
|
|
| DC7327 |
Tirofiban(L700462;MK383)
Featured
|
Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist. |
|
| DC7519 |
Torcetrapib
Featured
|
Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3. |
|
| DCAPI1452 |
Valsartan |
Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation. |
|
| DC8916 |
Vanoxerine dihydrochloride
Featured
|
Vanoxerine 2 Hcl(GBR12909) is a potent and selective DRI (Dopamine reuptake inhibitor). |
|
| DC7699 |
VTP-27999
Featured
|
VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. |
|
| DC7040 |
WAY-362450 (XL335; Turofexorate isopropyl)
Featured
|
WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia. |
|
| DC7753 |
Zatebradine hydrochloride |
Zatebradine hydrochloride is a bradycardic agent that creates use-dependent inhibition of hyperpolarization-activated current (If) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. |
|
| DC9461 |
Zatebradine |
Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
|
|
| DC9113 |
Ketanserin |
|
|
| DC9178 |
Ketanserin Tartrate |
|
|
| DC8860 |
Vorapaxar
Featured
|
Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM. |
|
| DC8901 |
Azilsartan medoxomil
Featured
|
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. |
|
