| DC9174 |
Cinepazide maleate |
Cinepazide Maleate is a vasodilator. |
|
| DC11098 |
CKD-519 |
CKD-519 (Rocacetrapib, CKD519) is a potent, selective cholesteryl ester transfer protein (CETP) inhibitor, inhibits the CETP-mediated transfer of cholesteryl ester in human serum with IC50 of 2.3 nM. |
|
| DC9380 |
Cleviprex
Featured
|
Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
|
|
| DC3147 |
Clopidogrel hydrogensulfate |
Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent. |
|
| DCAPI1417 |
Clopidogrel |
Clopidogrel is an irreversible inhibitor of the P2Y12 receptor, which is responsible for initiating signal transduction via a GPCR. The signal cascade initiates platelet aggregation and thus clopidogrel has the effect of “thinning” the blood. |
|
| DC8913 |
Dabigatran etexilate mesylate
Featured
|
Dabigatran etexilate mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. |
|
| DC7397 |
Darapladib
Featured
|
Darapladib is a selective and orally active inhibitor of Lp-PLA2 (IC50= 270 pM) |
|
| DCAPI1152 |
Diltiazem HCl (Tiazac) |
Diltiazem HCl (Tiazac) |
|
| DC10446 |
(3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride
Featured
|
Diltiazem hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). |
|
| DCAPI1457 |
Dronedarone Hydrochloride |
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium and sodium and is a calcium channel protein inhibitor. |
|
| DC9595 |
E-4031
Featured
|
E-4031 is a benzenesulfonamide antiarrhythmic agent; blocks the ATP-sensitive potassium channel.
|
|
| DC8533 |
E5555 hydrobromide |
E5555 shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC values of 0.064 and 0.031 μM respectively. |
|
| DC8305 |
Edoxaban
Featured
|
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention |
|
| DC8793 |
Edoxaban tosylate monohydrate
Featured
|
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention |
|
| DC7772 |
Elinogrel |
Elinogrel is a reversible P2Y12 receptor antagonist for the treatment of acute coronary syndrome and prevention of secondary thrombotic events. |
|
| DC7125 |
Evacetrapib (LY2484595)
Featured
|
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. |
|
| DCAPI1084 |
Ezetimibe (Zetia)
Featured
|
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. |
|
| DC9086 |
Fenofibrate |
Fenofibrate is PPARα agonist with EC50 of 18 μM and 30 μM for mouse and human PPARα, respectively. |
|
| DC9623 |
Flecainide (acetate)
Featured
|
Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
|
|
| DCAPI1596 |
Metroprolol succinate |
For the detailed information of Metroprolol succinate, the solubility of Metroprolol succinate in water, the solubility of Metroprolol succinate in DMSO, the solubility of Metroprolol succinate in PBS buffer, the animal experiment (test) of Metroprolol succinate, the cell expriment (test) of Metroprolol succinate, the in vivo, in vitro and clinical trial test of Metroprolol succinate, the EC50, IC50,and Affinity of Metroprolol succinate, Please contact DC Chemicals.. |
|
| DC10947 |
FPL64176
Featured
|
FPL64176 is a potent L-type Ca++ channel activator with EC50 of 16 nM. |
|
| DC7422 |
GSK1292263
Featured
|
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes. |
|
| DC10233 |
Guanfacine Hydrochloride |
Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect. |
|
| DC4233 |
GW501516
Featured
|
GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. |
|
| DC7707 |
LCZ-696
Featured
|
LCZ696 is a first-in-class dual inhibitor of the angiotensin II receptor(AT II receptor) and neprilysin; a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). |
|
| DC9123 |
Lisinopril Dihydrate |
Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. |
|
| DCAPI1419 |
Losartan |
Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II. |
|
| DC9153 |
Losartan Potassium
Featured
|
Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
|
| DC7711 |
Losmapimod
Featured
|
Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. Phase 3. |
|
| DC2072 |
LXR623
Featured
|
LXR-623 is a novel Liver X Receptor modulator |
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