Cat. No. | Product name | CAS No. |
DC7772 |
Elinogrel
Elinogrel is a reversible P2Y12 receptor antagonist for the treatment of acute coronary syndrome and prevention of secondary thrombotic events. |
936500-94-6 |
DC7125 |
Evacetrapib (LY2484595)
Featured
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. |
1186486-62-3 |
DCAPI1084 |
Ezetimibe (Zetia)
Featured
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. |
163222-33-1 |
DC9086 |
Fenofibrate
Fenofibrate is PPARα agonist with EC50 of 18 μM and 30 μM for mouse and human PPARα, respectively. |
49562-28-9 |
DC9623 |
Flecainide (acetate)
Featured
Flecainide(Tambocor) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential. |
54143-56-5 |
DCAPI1596 |
Metroprolol succinate
For the detailed information of Metroprolol succinate, the solubility of Metroprolol succinate in water, the solubility of Metroprolol succinate in DMSO, the solubility of Metroprolol succinate in PBS buffer, the animal experiment (test) of Metroprolol succinate, the cell expriment (test) of Metroprolol succinate, the in vivo, in vitro and clinical trial test of Metroprolol succinate, the EC50, IC50,and Affinity of Metroprolol succinate, Please contact DC Chemicals.. |
98418-47-4 |
DC10947 |
FPL64176
Featured
FPL64176 is a potent L-type Ca++ channel activator with EC50 of 16 nM. |
120934-96-5 |
DC7422 |
GSK1292263
Featured
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes. |
1032823-75-8 |
DC10233 |
Guanfacine Hydrochloride
Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect. |
29110-48-3 |
DC4233 |
GW501516
Featured
GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. |
317318-70-0 |
DC7707 |
LCZ-696
Featured
LCZ696 is a first-in-class dual inhibitor of the angiotensin II receptor(AT II receptor) and neprilysin; a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). |
936623-90-4 |
DC9123 |
Lisinopril Dihydrate
Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. |
83915-83-7 |
DCAPI1419 |
Losartan
Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II. |
114798-26-4 |
DC9153 |
Losartan Potassium
Featured
Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
124750-99-8 |
DC7711 |
Losmapimod
Featured
Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. Phase 3. |
585543-15-3 |
DC2072 |
LXR623
Featured
LXR-623 is a novel Liver X Receptor modulator |
875787-07-8 |
DC8523 |
LY333531 Hydrochloride(Ruboxistaurin HCl)
Featured
LY-333,531 Hydrochloride is a potent, selective inhibitor of Protein Kinase C isozymes, PKC beta I (IC50 = 4.7 nM) and PKC beta II (IC50 = 5.9 nM). It is potentially beneficial for cancer research. |
169939-93-9 |
DC9190 |
Manidipine Dihydrochlorid
Manidipine 2Hcl (CV-4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM. |
89226-75-5 |
DC11315 |
Manidipine(CV-4093)
Manidipine is a dihydropyridine L- and T-type calcium channel blocker. |
89226-50-6 |
DC9191 |
Metoprolol tartrate
Metoprolol is a cardioselective β1-adrenergic blocking agent. |
56392-17-7 |
DC1009 |
Laropiprant
Featured
MK 0524 is a potent, selective DP1 receptor antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively. |
571170-77-9 |
DC9456 |
MK-0354
MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b. |
851776-28-8 |