Zatebradine hydrochloride|Purchase|DC CHEM

Cas No.:	91940-87-3
Synonyms:	UL-FS 49
SMILES:	O=C1N(CCCN(CCC2=CC=C(OC)C(OC)=C2)C)CCC3=CC(OC)=C(OC)C=C3C1.Cl
Formula:	C₂₆H₃₆N₂O₅^.HCl
M.Wt:	493.04
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Zatebradine hydrochloride is a bradycardic agent that creates use-dependent inhibition of hyperpolarization-activated current (If) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. Displays negative chronotropic activity in isolated guinea pig atria (EC50 of 13.4μM).. For the detailed information of Zatebradine hydrochloride, the solubility of Zatebradine hydrochloride in water, the solubility of Zatebradine hydrochloride in DMSO, the solubility of Zatebradine hydrochloride in PBS buffer, the animal experiment (test) of Zatebradine hydrochloride, the cell expriment (test) of Zatebradine hydrochloride, the in vivo, in vitro and clinical trial test of Zatebradine hydrochloride, the EC50, IC50,and affinity,of Zatebradine hydrochloride, Please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC9461	Zatebradine	Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
DC7753	Zatebradine hydrochloride	Zatebradine hydrochloride is a bradycardic agent that creates use-dependent inhibition of hyperpolarization-activated current (If) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres.