Cat. No. | Product name | CAS No. |
DC9789 |
Icaritin(Anhydroicaritin)
Featured
Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings. |
118525-40-9 |
DC9982 |
I-CBP112
Featured
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors CREBBP (CBP) and EP300 (IC50 = 0.142 and 0.625 μM, respectively). |
1640282-31-0 |
DC11303 |
CT7001 hydrochloride
Featured
ICEC0942 is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively. |
1805789-54-1 |
DC3130 |
ICG-001
Featured
ICG-001 is a small-molecule antagonist of b-catenin/TCF-mediated transcription (IC50 = 3 uM) and specifically downregulates the expression of a subset of b-catenin/TCF-responsive genes. ICG-001 binds specifically to cyclic AMP response element-binding pro |
780757-88-2 |
DC3115 |
ICI-118551
Featured
ICI-118,551 is a selective beta-2 (β2) adrenergic receptor antagonist.ICI binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. |
72795-01-8 |
DC7213 |
ICILIN
Featured
Icilin is a synthetic super-agonist of the transient receptor potential M8 (TRPM8) ion channel. |
36945-98-9 |
DC8817 |
Icotinib Hydrochloride
Featured
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). |
1204313-51-8 |
DC9639 |
iCRT 14
Featured
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). |
677331-12-3 |
DC10680 |
iCRT3
Featured
iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription. |
901751-47-1 |
DC20601 |
Idarubicin
Featured
Idarubicin Free Base is an orally administered anthracycline antineoplastic. The compound has shown activity against BREAST NEOPLASMS; LYMPHOMA; and LEUKEMIA. |
58957-92-9 |
DC8111 |
Idarubicin Hydrochloride
Featured
Idarubicin Hcl is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. |
57852-57-0 |
DC9970 |
IDE-1
Featured
IDE-1 induces definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 125 nM). |
1160927-48-9 |
DC9971 |
IDE-2
Featured
IDE-2 is a cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 223 nM for induction of Sox17 expression in ESCs). |
1136466-93-7 |
DC11782 |
IDF-11774
Featured
IDF-11774 is a novel hypoxia-inducible factor α (HIFα)-1 inhibitor with an IC50 of 3.65 μM. |
1429054-28-3 |
DC10538 |
IDH-305
Featured
IDH305 is an inhibitor of the citric acid cycle enzyme isocitrate dehydrogenase [NADP] cytoplasmic (isocitrate dehydrogenase 1; IDH1) with mutations at residue R132 (IDH1(R132)), with potential antineoplastic activity. |
1628805-46-8 |
DC10830 |
IDH-889
Featured
IDH889 is a potent and selective inhibitors of IDH1. IDH899 shows IDH (R132H) IC50 = 20 nM; Cell 2-HG IC50 = 14 nM. |
1429179-07-6 |
DC10098 |
IDO-IN-1
Featured
IDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM, shows activity in Hela cell (IC50=12 nM). |
914638-30-5 |
DC10421 |
IDO-IN-2
Featured
IDO-IN-2 is an IDO inhibitor extracted from patent WO/2015031295 A1, compound example 1, has IC50 values of 0.068 μM in HeLa cell and 0.16 μM in HEK293 cell. |
1668565-74-9 |
DC12541 |
iGOT1-01
Featured
iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM. |
882256-55-5 |
DC8872 |
Iguratimod
Featured
Iguratimod is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. |
123663-49-0 |
DC11258 |
IITZ-01
Featured
IITZ-01 is a novel potent lysosomotropic autophagy inhibitor, has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo. |
1807988-47-1 |
DC12547 |
GDC-0214(GDC0214)
Featured
GDC0214 is a potent, selective inhalable and lung-restricted inhibitor of JAK1 with IC50 of 8.52 nM, displays 6.3/704/28 fold selectivity over JAK2/JAK3/TYK2. |
1831144-46-7 |