SMU127|SMU-127;ZINC666243

Cas No.:	903864-87-9
Chemical Name:	ethyl 2-(4-methylpiperazine-1-carboxamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
Synonyms:	SMU-127;ZINC666243
SMILES:	C12CCCC=1C(C(OCC)=O)=C(NC(N1CCN(C)CC1)=O)S2
Formula:	C₁₆H₂₃N₃O₃S
M.Wt:	337.438
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

SMU127 (SMU-127, ZINC666243) is a specific TLR1-TLR2 small molecule agonist with EC50 of 0.55 uM; stimulates NF-κB activation and promotes TNFα secretion in human macrophages and mononuclear cells, inhibits the growth of breast cancer tumors in BABL/c mice.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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