| DC8544 |
MI-463
Featured
|
MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction. |
|
| DC8545 |
MI-503
Featured
|
MI-503 is a highly potent and orally bioavailable small molecule inhibitor of the menin-MLL interaction. |
|
| DC10287 |
MI-538
Featured
|
MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. |
|
| DC8414 |
MI-77301 (SAR405838)
Featured
|
MI-77301 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1. |
|
| DCAPI1514 |
Micafungin sodium
Featured
|
Micafungin(FK463) is an echinocandin antifungal drug, Micafungin inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. |
|
| DC11162 |
MID-1
Featured
|
MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction; increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation; potent |
|
| DC23570 |
MIDD0301
Featured
|
MIDD0301 is a potent, positive allosteric, α5β3γ2 selective, GABAA receptor (GABAAR) ligand with EC50 of 17 nM, shows no significant binding at the peripheral GABAAR at 10 uM. |
|
| DC24075 |
Midodrine
Featured
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
|
| DC24076 |
Midodrine hydrochloride
Featured
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
|
| DC10328 |
Migalastat hydrochloride
Featured
|
Migalastat hydrochloride (1-Deoxygalactonojirimycin hydrochloride) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. |
|
| DC9545 |
Miglustat (hydrochloride)
Featured
|
Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). |
|
| DCAPI1436 |
Milbemycin oxime
Featured
|
Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~70: 30 ratio). Moxidectin oxime, marketed as Interceptor, is used therapeutically for the prev |
|
| DC3158 |
Milrinone
Featured
|
Milrinone(Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDE |
|
| DC9120 |
Miltefosine
Featured
|
Miltefosine is an alkylphosphocholine drug. |
|
| DC21584 |
MIN-101
Featured
|
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.. |
.gif)
|
| DC8928 |
Minocycline hydrochloride
Featured
|
Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. |
|
| DC10152 |
Miquelianin (Quercetin 3-O-glucuronide)
Featured
|
Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid. |
|
| DC3172 |
Mirabegron
Featured
|
Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM. |
|
| DC9275 |
Mirin
Featured
|
Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11. |
|
| DC23113 |
Mirk-IN-1
Featured
|
Mirk-IN-1 is a potent, specific inhibitor of Dyrk1B (Mirk kianse) and Dyrk1A with IC50 of 68 nM and 22 nM respectively, shows SW620 cell IC50 of 1.9 uM. |
|
| DC10013 |
Mirogabalin
Featured
|
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
|
| DC10532 |
Mirogabalin besylate
Featured
|
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
|
| DC10568 |
Mitapivat
Featured
|
Mitapivat is an activator of pyruvate kinase isoenzyme M2 (PKM2), |
|
| DC12625 |
MitoBloCK-10
Featured
|
MitoBloCK-10 (MB-10) is a potential attenuator of protein import into mitochondria via targeting Tim44, inhibits the import of substrates that use the TIM23 import pathway. |
|
| DC12626 |
MitoBloCK-11
Featured
|
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development. |
|
| DC8935 |
Mitomycin C
Featured
|
Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. |
|
| DC12364 |
Mito-TEMPO
Featured
|
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic with superoxide and alkyl radical scavenging properties. |
|
| DC9836 |
Mivebresib(ABBV-075）
Featured
|
Mivebresib is a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. |
|
| DC20978 |
Mizagliflozin
Featured
|
Mizagliflozin (DSP-3235, KGA-3235, GSK-1614235) is a potent, selective, orally active SGLT1 inhibitor with Ki of 27 nM, displays >350-fold selectivity over SGLT2. |
|
| DC9011 |
Mizoribine
Featured
|
Mizoribine(NSC 289637; HE 69; β-Bredinin) is an immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH. |
|
