Olacaftor

  Cat. No.:  DC11096  
Chemical Structure
1897384-89-2
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More than 5000 active chemicals with high quality for research!
Field of application
Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis..
Cas No.: 1897384-89-2
Chemical Name: N-(benzenesulfonyl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
Synonyms: VX-440;VX440
SMILES: C(N1C[C@H](C)CC1(C)C)1=NC(C2=CC(OCC(C)C)=CC(F)=C2)=CC=C1C(NS(C1=CC=CC=C1)(=O)=O)=O
Formula: C29H34FN3O4S
M.Wt: 539.666
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC11096 Olacaftor Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis..
DC11678 GLPG-2222 GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.
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