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Galnac Molecules

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Cat. No. Product Name Field of Application Chemical Structure
DC46965 Tri-GalNAc-COOH Featured tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research.
DC47877 tri-GalNAc-COOH (acetylation) Featured tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC.
DC71975 TriGalNAc CBz Featured TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies.
DC72269 Tri-GalNAc(OAc)3 TFA Featured Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera.
DC72546 Tri-GalNAc-NHS ester Featured Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC.
DC65560 GalNAc-L96 free base Featured GalNAc-L96 free base, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs.
DC65559 GalNAc-L96 Phosphoramidite Featured
DC65561 GalNac-L96 analog Featured GalNAc-L96 analog is an intermediate in the synthesis of the asialoglycoprotein receptor (ASGPR) ligand GalNAc-L96.
DC65562 GalNAc-NAG-25 Phosphoramidite Featured
DC65563 GalNAc-L96-CPG Featured
DC65564 GalNAc-L96-PS Featured
DC65565 GalNac-L96 Featured GalNac-L96, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs[1].
DC65965 Tri-GalNAc(OAc)3 Featured Tri-GalNAc(OAc)3 is a triantenerrary N-acetylgalactosamine (tri-GalNAc) with an amino group, which is useful precursor for synthesis of GalNAc-LYTAC that engage the asialoglycoprotein receptor for targeted protein degradation. Tri-GalNAc(OAc)3 was first reported in Nat Chem Biol. 2021 Sep;17(9):937-946 (compound ). This product has no formal name at the moment.
DC66548 GalNAc-Lipid GL3 Featured
DC66549 GalNAc-NAG-37 Phosphoramidite Featured
DC66550 GalNAc-Cluster-COOH Featured
DC66551 GalNAc-Cluster-HHA-CE Phosphoramidite Featured
DC66555 GalNAc-L96 Linker-Acid Featured
DC66557 GalNAc-L96 Linker-Azide Featured
DC66559 Peracetylated GalNAc PEG linker-Azide Featured
DC66560 GalNAc-L96-tert-butyl ester Featured GalNAc-L96-tert-butyl ester is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
DC66561 Peracetylated GalNAc succinimidyl pentanoate Featured
DC66564 Peracetylated GalNAc PEG linker-Acid-1 Featured
DC66565 Peracetylated GalNAc-L96-Acid-1 Featured
DC66568 Peracetylated GalNAc PEG linker-Amino-1 Featured
DC66569 GalNAc-L96-Amide Featured
DC66572 Peracetylated GalNAc PEG linker-Amino-2 Featured
DC66574 Peracetylated GalNAc-L96-1 Featured
DC66575 Peracetylated GalNAc PEG linker-Acid-2 Featured
DC67296 Galnac GLS-15 Featured GLS-15 is a novel GalNAc-derived small molecule structure designed for siRNA delivery.

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