Cas No.: | 1159408-61-3 |
Chemical Name: | NND-228102 |
Synonyms: | 1-[(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] butanedioate |
SMILES: | C(C1C=CC=CC=1)(C1C=CC(=CC=1)OC)(C1C=CC(=CC=1)OC)OC[C@@H]1C[C@H](CN1C(=O)CCCCCCCCCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1NC(=O)C)OC(=O)C)OC(=O)C)COC(=O)C)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1NC(=O)C)OC(=O)C)OC(=O)C)COC(=O)C)COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1NC(=O)C)OC(=O)C)OC(=O)C)COC(=O)C)OC(=O)CCC(=O)O |
Formula: | C121H179N11O45 |
M.Wt: | 2507.76 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | GalNac-L96 free base, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs. |
References: | [1]. Anna Clua, et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules. 2022 Jun 20;27(12):3944. |