Cat. No. | Product name | CAS No. |
DC11974 |
L 741742 hydrochloride
A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors. |
874882-93-6 |
DC11743 |
BMS-681
A potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively. |
847998-92-9 |
DC11705 |
GPR30 inhibitor G1
Featured
A potent and selective GPER/GPR30 agonist with Ki of 11 nM, EC50 of 2 nM. |
881639-98-1 |
DC11699 |
VUF11403
A potent CXCR7 (ACKR3) agonist.. |
1378524-61-8 |
DC11976 |
SX-576
A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively. |
1240494-14-7 |
DC11903 |
NBUMP
A potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.. |
1348755-27-0 |
DC11609 |
VU6010608
A potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM. |
2165325-42-6 |
DC11758 |
PB 28 dihydrochloride
Featured
A potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
172907-03-8 |
DC11757 |
PB 28
A potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
172906-90-0 |
DC11629 |
NK1-IN-9
A potent, orally active, dual NK1 receptor antagonist (IC50=0.5 nM) and SERT inhibitor (IC50=5.2 nM). |
1100211-97-9 |
DC11697 |
AM-1638
A potent, orally bioavailable, full agonist of GPR40/FFA1 with EC50 of 0.16 uM. |
1142214-62-7 |
DC11979 |
SB 332235
A potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92. |
276702-15-9 |
DC11755 |
L-732138
Featured
A potent, selective and competitive NK1 receptor antagonist with IC50 of 2.3 nM. |
148451-96-1 |
DC11514 |
Atogepant
A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine. |
1374248-81-3 |
DC11519 |
Ceclazepide
A potent, selective cholecystokinin receptor CCK2 antagonist for treatment of gastroesophageal reflux disease (GERD).. |
1801749-44-9 |
DC12015 |
SKF 83566 hydrobromide
A potent, selective dopamine D1 receptor antagonist with Ki of 0.56 nM. |
108179-91-5 |
DC11973 |
A-412997
A potent, selective dopamine D4 receptor agonist with Ki of 12.1 and 7.9 nM for rat and human D4 receptors, respectively. |
1347744-96-0 |
DC11700 |
Chalcone 4 hydrate
A potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM. |
1202866-96-3 |
DC11560 |
SPM-242
A potent, selective S1P3 antagonist with Ki of 0.25 nM. |
|
DC11561 |
SPM-242 racemate
A potent, selective S1P3 antagonist with Ki of 0.25 nM. |
749263-43-2 |
DC11745 |
BMS-22
A potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM. |
445479-97-0 |
DC11744 |
CCR2-RA-[R]
A potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM.. |
512177-83-2 |