| DC11698 |
α-NETA |
A small molecule CMKLR1 antagonist that inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 (EC50=9.7 nM). |
|
| DC9867 |
prostaglandin D2（PGD2) inhibitor
Featured
|
A small molecule compound of prostaglandin D2（PGD2) inhibitor. |
|
| DC11686 |
(R)-CCX-777 |
A small-molecule partial agonist of CXCR7 (ACKR3).. |
|
| DC11687 |
(S)-CCX-777 |
A small-molecule partial agonist of CXCR7 (ACKR3).. |
|
| DC11685 |
CCX-777 |
A small-molecule partial agonist of CXCR7 (ACKR3).. |
|
| DC11525 |
Mocravimod |
A synthetic immunosuppressant that functions as a S1P1 receptor agonist. |
|
| DC8667 |
AB-MECA
Featured
|
AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors. |
|
| DC10293 |
AC260584 |
AC260584 is an M1 muscarinic receptor allosteric agonist with a pEC50 of 7.6. |
|
| DC10117 |
AC264613
Featured
|
AC264613 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 7.5). Displays no activity at other PAR subtypes and exhibits no significant activity at over 30 other receptors implicated in nociception and inflammation. |
|
| DC10279 |
Acrivastine |
Acrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis. |
|
| DC11209 |
ACT-246475 |
ACT-246475 (ACT246475) is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
|
| DC11439 |
Nemorexant
Featured
|
ACT-541468 is a dual orexin receptor antagonist. |
|
| DC8191 |
Sparsentan(PS433540)
Featured
|
Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1]. |
|
| DC11754 |
AD 2900
Featured
|
AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively. |
|
| DC7050 |
ADL5859 HCl
Featured
|
ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.ADL5859 displays weak inhibitory activity at the hERG channel with an IC50 of 78 μM. The EC50 of ADL5859 against δ opioid |
|
| DC8087 |
ADX 47273
Featured
|
ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM. |
|
| DC10465 |
ADX-88178
Featured
|
ADX-88178 is a novel potent, selective, and brain-penetrant positive allosteric modulator of the mGlu4 receptor. |
|
| DC12213 |
AGN 210676 (Simenepag) |
AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. |
|
| DC11005 |
AGN192836 |
AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. |
|
| DC3171 |
Agomelatine |
Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. |
|
| DCAPI1467 |
Alcaftadine |
Alcaftadine |
|
| DC9334 |
Alfuzosin |
Alfuzosin is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH).
|
|
| DC7692 |
Almorexant HCl (Act-078573)
Featured
|
Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. |
|
| DC8284 |
Almotriptan Malate(PNU180638)
Featured
|
Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine. |
|
| DC10234 |
Alosetron Hydrochloride |
Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. |
|
| DC8606 |
Alvimopan monohydrate |
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
|
| DC8605 |
Alvimopan dihydrate |
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
|
| DC8621 |
AM095
Featured
|
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. |
|
| DC8622 |
AM095 free acid
Featured
|
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. |
|
| DC12230 |
AM211
Featured
|
AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist |
|
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