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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC2635 Ibpr002 Novel Aurora kinase inhibitor, revealing mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
DCC2636 Ibrutinib-bfl Novel fluorescent irreversible inhibitor of Bruton's tyrosine kinase (BTK)
DCC2637 Ibs399024 Novel HDAC6-selective inhibitor
DCC2638 Ic2418 MmpL3 inhibitor, being active against drug-resistant Mycobacterium tuberculosis
DCC2639 ica-27243 Neuronal Kv7 potassium channel activator
DCC2640 Icagen-4 Inhibitor of voltage-gated K(+) (Kv) channels Kv1.3 and Kv1.5
DCC2641 Ical-36 Novel inhibitor of CALP, exhibiting affinity of 22.6 ± 8.0 μM for CALP and no interaction with the NHERF PDZ domains
DCC2642 icec0943 Novel selective inhibitor of CDK7
DCC2643 Ici-185282 Potent thromboxane receptor antagonist
DCC2644 Ici-56780 Antimalarial agent, displaying blood schizonticidal activity against P.berghei
DCC2645 Iclaprim Novel selective bacterial dihydrofolate inhibitor, antibiotic, actively against Gram positive organisms
DCC2646 Icl-ccic-0019 Novel potent and selective inhibitor of choline kinase alpha (CHKA)
DCC2647 Icl-sirt078 Novel highly selective, substrate-competitive SIRT2 inhibitor, displaying a significant neuroprotective effect in a lactacystin-induced model of Parkinsonian neuronal cell death in the N27 cell line
DCC2648 Icpd62 Novel inhibitor of heat shock protein 90 (Hsp90), demonstrating anticancer activity against colorectal, osteosarcoma and cervical cancer cell lines
DCC2649 Icrf-193 DNA topoisomerase II inhibitor
DCC2650 Ict2700 Potent cytotoxin selectively by CYP1A1 as a tumor-selective treatment for human bladder cancers
DCC2651 Id110460001 Novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist
DCC2652 Id110460002 Novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist
DCC2653 Id110460003 Novel μ,δ-Opioid Receptor Dual-Biased Agonist, Overcoming the Limitation of Prior Biased Agonist
DCC2654 idaverine M1 and M2 Antagonist
DCC2655 Ide-in-37 Tfa Salt Novel highly potent substrate-selective inhibitor of insulin-degrading enzyme (IDE), blocking insulin binding while allowing glucagon cleavage, even at saturating inhibitor concentrations
DCC2656 Ide-in-63 Tfa Salt Novel highly potent substrate-selective inhibitor of insulin-degrading enzyme (IDE), blocking insulin binding while allowing glucagon cleavage, even at saturating inhibitor concentrations
DCC2657 Idh2 Inhibitor Novel isocitrate dehydrogenase 2 (IDH2) mutants inhibitor for the treatment of cancer
DCC2658 Idi-3783 Novel mutant-selective Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor
DCC2659 Ido1/2 Inhibitor 4t The first inhibitor targeting both IDO1/2 that has excellent in vitro inhibitory activity (IDO1 IC50 = 28 nM and IDO2 IC50 = 144 nM)
DCC2660 idoxifene Selective ER modulator (SERM)
DCC2661 Idr-0081053 Novel bactericidal agent against M. tuberculosis under acidic conditions, being effective at sterilizing cultures in a concentration-dependent fashion at the highest concentrations
DCC2662 Idr-0099118 Novel concentration dependent bactericidal agent against M. tuberculosis, being markedly more efficient at killing M. tuberculosis under acidic conditions
DCC2663 Idr-1002 Innate Defence Regulator Peptide, Enhancing Monocyte Migration and Adhesion on Fibronectin
DCC2664 Idr-1018 Tfa Salt Novel immunomodulatory and antibiofilm innate defense regulator peptide

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