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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DCC4706 Sgk1 Inhibitor 17a Novel highly selective SGK1 inhibitor with a highly optimized profile suitable for oral dosing as a potentially disease-modifying agent for osteoarthritis
DCC4707 Sglt1/2-in-8 Novel Potent SGLT1/2 Dual Inhibitor
DCC4708 Sgx393 Novel inhibitor of the CML mutant Bcr-AblT315I, preempting in vitro resistance when combined with nilotinib or dasatinib.
DCC4709 Sh-053-r-ch3-2’f Selective agonist of GABA A receptors α5 subunit
DCC4710 Sh-053-s-ch3-2'f Potent and selective agonist of GABAA receptors α5 subunit
DCC4711 Sh-11037 Novel potent sEH inhibitor, effectively blocking key angiogenic properties of human retinal endothelial cells (HRECs), inhibiting choroidal sprouting and significantly suppressing CNV lesion volume
DCC4712 Sh-11052 Novel inhibitor of endothelial cell growth
DCC4713 Sh-2251 Novel selective inhibitor of the generation of IL-5-producing Th2 cells and induction of active histone modifications at the IL5 gene locus during Th2 cell differentiation
DCC4714 Sha 14-1 Stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypassing drug resistances and synergizing cancer therapies in human leukemia cell
DCC4715 She-196 First in Class Hypoglycemic Agent with Extra-Strong Action, increasing insulin sensitivity, improving glucose tolerance, reducing fasted insulin level and insulin sensitivity, decreasing total body and interscapular fat mass and also increasing the activi
DCC4716 Sherpa Bmi-135 Novel Selective Human ER Partial Agonist (ShERPA)
DCC4717 Sheta2 Selective inhibitor of cancer cell growth, exerting chemoprevention activity without evidence of toxicity
DCC4718 Sh-i-14 Novel Inhibitor of Phospho-STAT3 Through Induction of Protein Tyrosine Phosphatase PTPN6
DCC4719 Shield-2 Novel potent stabilizing ligand for FKBP-derived destabilizing domains
DCC4720 Ship-2a Cystathione gamma lyase (CSE) inhibitor, inhibiting H2S production and L-cysteine-induced relaxation of rat aortic rings ex vivo
DCC4721 Showdomycin Antineoplastic antibiotic
DCC4722 Shp2 Inhibitor C21 Inhibitor of shp2 protein tyrosine phosphatase (PTP)
DCC4723 Shr0687 Highly Potent and Peripheral Nervous System-Restricted KOR Agonist
DCC4724 Sibopirdine Novel cognitive enhancer; Nootropic agent
DCC4725 Sid-24784551 Novel direct HIV-1 Nef antagonist with antiretroviral activity
DCC4726 Sid-7977382 Novel Complement Factor C1 Inhibitor
DCC4727 Silagaba132 Silicon-Containing GABA Derivative, Treating Neuropathic Pain without Central-Nervous-System-Related Side Effects
DCC4728 Silagaba161 Silicon-Containing GABA Derivative, Treating Neuropathic Pain without Central-Nervous-System-Related Side Effects
DCC4729 Sila-ibuprofen Novel COX-I and COX-II inhibitor with four times higher solubility in physiological media and a lower melting enthalpy than ibuprofen
DCC4730 Simfibrate Peroxisome proliferator
DCC4731 Sinapine Sulfate Antioxidant and antimicrobial agent, counteracting mitochondrial oxidative stress in cardiomyocytes
DCC4732 Sipi-6360 Novel D2/5-HT2A Receptor Dual Antagonist
DCC4733 Sipi-7623 Novel farnesoid X receptor antagonist
DCC4734 Sirt1-a2 Novel SIRT1 Activator
DCC4735 Sirt1-enhancer-a03 First-in-class apolipoprotein E4 (ApoE4)-targeted sirtuin1 (SirT1) enhancer, normalizing sirtuin 1 levels and improving cognition in an Alzheimer's disease mouse model

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