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(S)-BI 665915

Cat. No.: DC28608

Chemical Structure

1360550-05-5

For research use only. We do not sell to patients.

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Field of application

(S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC50 of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species drug metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB4 production.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	1360550-05-5
Formula:	C₂₄H₂₆N₈O₂
M.Wt:	458.52
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

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MSDS_12660_DC28608_1360550-05-5

COA

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Cat. No.	Product name	Field of application
DC28965	Veliflapon	Veliflapon (BAY X 1005; DG-031) is an orally active and selective 5-lipoxygenase activating protein (FLAP) inhibitor. Veliflapon inhibits the synthesis of the leukotrienes B4 and C4.
DC28608	(S)-BI 665915	(S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC50 of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species drug metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB4 production.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.